{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:40:15Z","timestamp":1789501215869,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Post\u2010tuberculosis lung disease (PTLD) is a precursor to\n                      <jats:italic>Aspergillus<\/jats:italic>\n                      \u2010related lung diseases. While Chronic Pulmonary Aspergillosis (CPA) has been extensively studied in the background of tuberculosis, Allergic Bronchopulmonary Aspergillosis (ABPA) has been reported sporadically with limited information on its prevalence, clinical\u2010radiological features, and treatment outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study, conducted in a high TB burden setting, aimed to address this knowledge gap by systematically evaluating ABPA in PTLD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study screened PTLD patients presenting with respiratory or constitutional symptoms persisting for more than 3\u2009months. The objective was to report the prevalence, clinical\u2010radiological\u2010laboratory data, and outcomes of ABPA\u2010PTLD compared to a cohort of CPA (CPA\u2010PTLD) and patients with PTLD (PTLD only).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of a total of 1012 PTLD patients, ABPA was seen in 2.27%, CPA in 20.75% and\n                      <jats:italic>Aspergillus<\/jats:italic>\n                      sensitization in 0.7%. ABPA patients primarily presented with breathlessness (91.3%) and cough (82.6%) while haemoptysis (43.5%), weight loss (13%), and anorexia (21.7%) were also observed, albeit less commonly than in CPA\u2010PTLD. Bronchiectasis (100%) and nodules (87%) were more frequent in ABPA\u2010PTLD patients, whereas consolidation (21.7%), cavities (30.4%), pleural thickening (8.7%), and \u2018fungal ball\u2019 (9.1%) were also seen, although less commonly than in CPA\u2010PTLD. Most patients received azoles (78%) as first\u2010line therapy, with symptomatic improvement (partial\/complete) observed in ~78%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ABPA may occur in PTLD patients, with specific clinical (e.g., haemoptysis) and radiological (e.g., cavity and fungal ball) features uncommon in other types of ABPA, but resembling other PTLD conditions. Future studies should focus on identifying differences in the natural course and appropriate treatment paradigms of ABPA\u2010PTLD patients compared to ABPA occurring in asthma and cystic fibrosis patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/myc.70034","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T23:04:16Z","timestamp":1739919856000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Allergic Bronchopulmonary Aspergillosis in Patients With Prior Pulmonary Tuberculosis: A Study on the Burden, Clinic\u2010Radiological Features, Treatment Outcomes and Comparison With Chronic Pulmonary Aspergillosis and Post\u2010Tubercular Lung Disease Patients"],"prefix":"10.1111","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7909-3259","authenticated-orcid":false,"given":"Anuj","family":"Ajayababu","sequence":"first","affiliation":[{"name":"Department of Medicine and Microbiology AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ved Prakash","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prayas","family":"Sethi","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranveer Singh","family":"Jadon","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gagandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Microbiology AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Immaculata","family":"Xess","sequence":"additional","affiliation":[{"name":"Department of Microbiology AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6392-6578","authenticated-orcid":false,"given":"Stanzin","family":"Spalkit","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeraj","family":"Nischal","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surabhi","family":"Vyas","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveet","family":"Wig","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9434-5338","authenticated-orcid":false,"given":"Animesh","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Medicine AIIMS  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"WHO \u201cGlobal Tuberculosis Reports \u201d2024 https:\/\/www.who.int\/teams\/global\u2010tuberculosis\u2010programme\/tb\u2010reports."},{"issue":"4","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2018-000745","article-title":"International Research and Guidelines on Post\u2010Tuberculosis Chronic Lung Disorders: A Systematic Scoping Review","volume":"3","author":"Kampen S. 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