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The available data have been compiled and sometimes re\u2010analysed. It highlights the increasing prevalence of resistance in non\u2010\n                    <jats:italic>fumigatus<\/jats:italic>\n                    species belonging to Flavi, Terrei, Nigri, and Nidulantes\n                    <jats:italic>Aspergillus<\/jats:italic>\n                    sections, offering a detailed analysis of resistance detection methods and the global distribution of resistant strains. The review also thoroughly examines the molecular mechanisms behind resistance and raises key unresolved issues, such as the factors contributing to resistance selection and the clinical implications of in\u00a0vitro resistance. Additionally, it addresses the challenges of treating infections caused by resistant\n                    <jats:italic>Aspergillus<\/jats:italic>\n                    species and cryptic species and discusses current and future strategies relying on combination therapy and newly developed antifungals. The conclusion emphasises the need for further research into resistance mechanisms and alternative treatments to address the rising threat of antifungal resistance in\n                    <jats:italic>Aspergillus<\/jats:italic>\n                    species.\n                  <\/jats:p>","DOI":"10.1111\/myc.70051","type":"journal-article","created":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T04:27:36Z","timestamp":1744432056000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Antifungal Resistance in Non\u2010\n                    <i>fumigatus Aspergillus<\/i>\n                    Species"],"prefix":"10.1111","volume":"68","author":[{"given":"Elie","family":"Djenontin","sequence":"first","affiliation":[{"name":"UR 7380 Dynamyc UPEC, EnvA, ANSES Facult\u00e9 de Sant\u00e9 de Cr\u00e9teil  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose\u2010Anne","family":"Lavergne","sequence":"additional","affiliation":[{"name":"UR 1155 Cibles et M\u00e9dicaments Des Infections et de L'immunit\u00e9, IICiMed Nantes Universit\u00e9, CHU Nantes  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5859-6105","authenticated-orcid":false,"given":"Florent","family":"Morio","sequence":"additional","affiliation":[{"name":"UR 1155 Cibles et M\u00e9dicaments Des Infections et de L'immunit\u00e9, IICiMed Nantes Universit\u00e9, CHU Nantes  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Dannaoui","sequence":"additional","affiliation":[{"name":"UR 7380 Dynamyc UPEC, EnvA, ANSES Facult\u00e9 de Sant\u00e9 de Cr\u00e9teil  Cr\u00e9teil France"},{"name":"Unit\u00e9 de Parasitologie\u2010Mycologie, Service de Microbiologie H\u00f4pital Necker, AP\u2010HP  Paris France"},{"name":"Facult\u00e9 de M\u00e9decine Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2018.26"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.11.027"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/life14010001"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof9040500"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof5030055"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fgb.2019.103247"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens12111305"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579\u2010022\u201000720\u20101"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes11101217"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.simyco.2021.100115"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2007\/007641\u20100"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01280\u201007"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms12050886"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05178\u201011"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab392"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01927\u201017"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0064871"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00632\u201019"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa230"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00642\u201007"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.24971"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00304\u201011"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.funbio.2016.02.006"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046\u2010024\u201000869\u20108"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00069\u201019"},{"key":"e_1_2_7_27_1","unstructured":"P. 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