{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:50:16Z","timestamp":1791557416328,"version":"4.3.4"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2504804"],"award-info":[{"award-number":["2022YFC2504804"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2504800"],"award-info":[{"award-number":["2022YFC2504800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Trichophyton mentagrophytes<\/jats:italic>\n                      ITS genotype VII (TMVII) has recently been identified as a cause of genital infections, raising concerns about its potential as an emerging sexually transmitted pathogen. However, the epidemiology and clinical features of TMVII infection remain poorly understood.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To systematically review published TMVII cases and characterise its demographic distribution, transmission patterns, clinical manifestations and treatment outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive literature review was conducted, including all published molecularly confirmed TMVII cases. Data on demographics, infection sites, co\u2010infections and treatments were extracted and analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 124 TMVII cases from 10 studies were included. Among 60 cases with detailed clinical data, tinea genitalis (36.7%) and tinea faciei\/barbae\/capitis (51.7%) were the common infection types. TMVII infection predominantly affected men who have sex with men (64%), with high co\u2010infection rates of HIV (29.6%) and gonorrhoea (42.6%). Most cases were reported in France (49%) and Germany (35%), suggesting possible local transmission. Oral terbinafine (250\u2009mg\/day for 4\u20138\u2009weeks) achieved a 64.4% cure rate (38\/59 courses), while limited data indicated itraconazole and griseofulvin were also effective. Fluconazole showed no therapeutic efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>TMVII can be transmitted through sexual activities, particularly affecting MSM and individuals with concomitant STDs. Current evidence suggests that oral terbinafine is effective, meanwhile other antifungals need further observation.\u00a0Increased focus is warranted on the clinical management and monitoring of TMVII infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/myc.70075","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T02:49:49Z","timestamp":1749523789000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Epidemiological and Clinical Profile Analysis of\n                    <i>Trichophyton mentagrophytes<\/i>\n                    <scp>ITS<\/scp>\n                    Genotype\n                    <scp>VII<\/scp>\n                    Infected Dermatomycosis: An Emerging Sexually Transmitted Pathogen"],"prefix":"10.1111","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7252-1097","authenticated-orcid":false,"given":"Yuhan","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Medical Mycology, Hospital for Skin Diseases, Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2738-7589","authenticated-orcid":false,"given":"Wenting","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology, Hospital for Skin Diseases, Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1936-3736","authenticated-orcid":false,"given":"Weida","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medical 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