{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:52:36Z","timestamp":1773273156231,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Taste dysfunction is a common symptom of oral candidiasis; however, its underlying mechanisms remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      This study aimed to determine whether\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Candida albicans<\/jats:italic>\n                      <\/jats:styled-content>\n                      carriage, particularly its hyphal phenotype, is associated with impaired taste sensitivity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Methods<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010seven participants were divided into three groups: noncarriers (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920), carriers without hyphae (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920), and carriers with hyphae (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200917). Tongue biofilm samples were collected for\n                      <jats:italic>Candida<\/jats:italic>\n                      culture and smear tests. Salivary flow rates were measured, and taste sensitivity was assessed using standardised taste strips. Carriers underwent topical fluconazole treatment, and post\u2010treatment taste sensitivity was re\u2010evaluated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Carriers exhibited reduced sensitivity to sweet and bitter tastes, with an additional decline in umami sensitivity among those with hyphae. In addition, both unstimulated and stimulated salivary flow rates were significantly lower in\n                      <jats:italic>Candida<\/jats:italic>\n                      carriers than in noncarriers. Topical fluconazole treatment resulted in a marked reduction in hyphae and significant improvement in taste sensitivity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This study revealed differences in salivary flow and taste sensitivity between noncarriers and\n                      <jats:styled-content style=\"fixed-case\">Candida albicans<\/jats:styled-content>\n                      carriers. The presence of hyphal forms was strongly associated with greater impairment in taste function. Improvement following antifungal therapy suggests that hyphal invasion may play a key role in the pathogenesis of taste dysfunction in oral candidiasis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/myc.70145","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T12:24:46Z","timestamp":1771590286000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Taste Dysfunction in Oral Candidiasis: Impact of\n                    <i>Candida<\/i>\n                    Carriage and Hyphal Presence"],"prefix":"10.1111","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9152-7849","authenticated-orcid":false,"given":"Younjung","family":"Park","sequence":"first","affiliation":[{"name":"Department of Orofacial Pain and Oral Medicine Yonsei University College of Dentistry  Seoul Republic of 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