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Following an overview of different imaging modalities, the present review will give a concise introduction to systematic image analysis and interpretation in genetic neuromuscular disorders. The pattern of selective muscle involvement will be presented in detail in conditions such as the congenital or myofibrillar myopathies where muscle imaging is particularly useful to inform the (differential) diagnosis, and in disorders such as Duchenne or fascioscapulohumeral muscular dystrophy where the diagnosis is usually made on clinical grounds but where detailed knowledge of disease progression on the muscle imaging level may inform better understanding of the natural history. Utilizing the group of the congenital myopathies as an example, selected case studies will illustrate how muscle MRI can be used to inform the diagnostic process in the clinico\u2010pathological context. Future developments, in particular, concerning the increasing use of whole\u2010body MRI protocols and novel quantitative fat assessments techniques potentially relevant as an outcome measure, will be briefly outlined.<\/jats:p>","DOI":"10.1111\/nan.12385","type":"journal-article","created":{"date-parts":[[2017,1,23]],"date-time":"2017-01-23T08:57:02Z","timestamp":1485161822000},"page":"24-43","source":"Crossref","is-referenced-by-count":36,"title":["Myopathology in times of modern imaging"],"prefix":"10.1111","volume":"43","author":[{"given":"H.","family":"Jungbluth","sequence":"first","affiliation":[{"name":"Department of Paediatric Neurology Neuromuscular Service Evelina's Children Hospital Guy's &amp; St. Thomas\u2019 Hospital NHS Foundation Trust London UK"},{"name":"Randall Division of Cell and Molecular Biophysics Muscle Signalling Section London UK"},{"name":"Department of Clinical and Basic Neuroscience IoPPN, King's College London 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