{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:08:05Z","timestamp":1789704485140,"version":"4.0.1"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropathology Appl Neurobio"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>We describe the case of a 32\u2010year\u2010old woman with focal drug\u2010resistant epilepsy who underwent surgical resection of a cerebral cavernous malformation (CCM) previously treated with laser interstitial thermal therapy (LITT), following seizure recurrence.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Histological findings after LITT have rarely been described.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>We report and discuss neuropathological findings that may explain post\u2010LITT seizure recurrence, focusing on extensive haemosiderin deposition and a small residual component of the original CCM.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>This illustrative case may improve understanding of the histological basis of LITT failure to provide sustained seizure control.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1111\/nan.70099","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:10:30Z","timestamp":1787015430000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neuropathological Findings Following Failure of Laser Interstitial Thermal Therapy for an Epileptogenic Cerebral Cavernous Malformation"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8745-4659","authenticated-orcid":false,"given":"Alberto","family":"Pietrantoni","sequence":"first","affiliation":[{"name":"Neuropathology Unit Fondazione IRCCS Istituto Neurologico Carlo Besta  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4202-955X","authenticated-orcid":false,"given":"Roberta","family":"Di Giacomo","sequence":"additional","affiliation":[{"name":"Epilepsy Unit Fondazione IRCCS Istituto Neurologico Carlo Besta  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7936-6536","authenticated-orcid":false,"given":"Michele","family":"Rizzi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Fondazione IRCCS Istituto Neurologico Carlo Besta  Milan 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Translational Medicine University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4508-3359","authenticated-orcid":false,"given":"Gianluca","family":"Marucci","sequence":"additional","affiliation":[{"name":"Neuropathology Unit Fondazione IRCCS Istituto Neurologico Carlo Besta  Milan 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