{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T04:48:24Z","timestamp":1772858904578,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nutrition Bulletin"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Maternal obesity and excessive gestational weight gain (EGWG) may have persistent effects on offspring obesity and be risk factors for both mother and child. Studies have reported that asprosin concentration is associated with metabolism and weight changes during pregnancy. This study therefore evaluated the association of maternal and newborn asprosin with normal weight gain and EGWG and nutritional intake in pregnancy. The study included 30 pregnant women with normal weight gain and 30 women with EGWG referred to Ali ibn Abi Talib Hospital in Zahedan, Iran, September 2020 to June 2021. A demographic questionnaire and neonatal complications checklist were completed. Asprosin concentrations at the time of delivery in maternal venous blood samples and umbilical vein blood samples were measured by ELISA technique. Macronutrient and energy intake were assessed by a 24\u2010h dietary recall questionnaire and compared with standard Recommended Dietary Allowance (RDA) and Dietary References Intake (DRI) values. Asprosin levels were significantly higher in the EGWG group's umbilical cord blood than in the control group but there was no difference in maternal asprosin concentrations between the two groups. The Appearance, Pulse, Grimace, Activity and Respiration (Apgar) score was significantly lower in the EGWG group than in the control group, although there was no difference in birthweight between the groups. Weight gain during pregnancy,\u00a0energy intake and protein and carbohydrate consumption were significantly higher in\u00a0the EGWG group than in the control group (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05). It seems that differences in asprosin secretion do not mediate an imbalance in energy intake and other macronutrients during pregnancy that affect pregnancy weight gain and birthweight. However, excessive gestational weight gain was associated with neonatal asprosin levels and newborn Apgar scores.<\/jats:p>","DOI":"10.1111\/nbu.12542","type":"journal-article","created":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T07:30:10Z","timestamp":1645169410000},"page":"50-56","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Association of maternal and umbilical cord blood asprosin with excessive gestational weight gain"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0408-0525","authenticated-orcid":false,"given":"Fatemeh","family":"Behrasi","sequence":"first","affiliation":[{"name":"Department of Nutrition School of Medicine Zahedan University of Medical Sciences Zahedan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9032-9330","authenticated-orcid":false,"given":"Mansour","family":"Karajibani","sequence":"additional","affiliation":[{"name":"Department of Nutrition Health Promotion Research Center School of Medicine Zahedan University of Medical Sciences Zahedan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samira","family":"Khayat","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Pregnancy Health Research Center School of Nursing and Midwifery Zahedan University of Medical Sciences Zahedan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamed","family":"Fanaei","sequence":"additional","affiliation":[{"name":"Department of Physiology Pregnancy Health Research Center School of Medicine Zahedan University of Medical Sciences Zahedan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzaneh","family":"Montazerifar","sequence":"additional","affiliation":[{"name":"Department of Nutrition Pregnancy Health Research Center School of Medicine Zahedan University of Medical Sciences Zahedan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/03670244.2016.1147437"},{"key":"e_1_2_11_3_1","first-page":"615","article-title":"The influence of gestational weight gain on the development of gestational hypertension in obese women","volume":"32","author":"Barton J.R.","year":"2015","journal-title":"American Journal of Perinatology"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2019.170132"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1602572"},{"key":"e_1_2_11_6_1","volume-title":"Gestational weight gain among women with full\u2010term, singleton births, compared with recommendations\u201048 states and the District of Columbia, 2015","author":"Branum A.M.","year":"2016"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms150916153"},{"key":"e_1_2_11_8_1","volume-title":"Weight gain during pregnancy: reexamining the guidelines","author":"Council N.R.","year":"2010"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4432"},{"key":"e_1_2_11_10_1","volume-title":"The assessment of relationship between excessive weight gain and urinary tract infection in pregnant women\u2010larestan\u20101387\u201088","author":"Ebadi M.","year":"2009"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/640291"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2007.00464.x"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.10999"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40348-020-00110-8"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2017.03.006"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/her\/cyy040"},{"key":"e_1_2_11_17_1","first-page":"1199","article-title":"Nutrition recommendations in pregnancy and lactation","volume":"100","author":"Kominiarek M.A.","year":"2016","journal-title":"Medical Clinics"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.12.4382"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2019.05.022"},{"key":"e_1_2_11_20_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/7375294","article-title":"Plasma asprosin levels are associated with glucose metabolism, lipid, and sex hormone profiles in females with metabolic\u2010related diseases","volume":"2018","author":"Li X.","year":"2018","journal-title":"Mediators of Inflammation"},{"key":"e_1_2_11_21_1","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.3760\/cma.j.issn.0366-6999.20132772","article-title":"Gestational weight gain and risk of gestational diabetes mellitus among Chinese women","volume":"127","author":"Liu Z.","year":"2014","journal-title":"Chinese Medical Journal"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500523"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114512002450"},{"key":"e_1_2_11_24_1","first-page":"609","article-title":"Weight gain and food group consumption patterns in pregnant women of north and east hospitals of Tehran","volume":"12","author":"Mohammadi M.","year":"2011","journal-title":"Iranian Journal of Endocrinology and Metabolism"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.7762\/cnr.2018.7.3.213"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.4161\/org.4.3.6503"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.obmed.2019.100111"},{"key":"e_1_2_11_28_1","volume-title":"Krause and Mahan's food & the nutrition care process","author":"Raymond J.L.","year":"2021"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.02.063"},{"key":"e_1_2_11_30_1","first-page":"43","article-title":"Relationship between Serum visfatin with anthropometric indices and maternal gestational weight gain","volume":"22","author":"Saber A.","year":"2019","journal-title":"The Iranian Journal of Obstetrics, Gynecology and Infertility"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801670"},{"key":"e_1_2_11_32_1","first-page":"1074","article-title":"Validation of diet history questionnaire in assessing energy and nutrient intakes of Iranian population","volume":"48","author":"Toorang F.","year":"2019","journal-title":"Iranian Journal of Public Health"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2521096"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002744"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1159\/000503808"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000559005.27543.69"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.126200"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2020.02.004"}],"container-title":["Nutrition Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nbu.12542","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nbu.12542","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nbu.12542","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T21:25:46Z","timestamp":1726694746000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nbu.12542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,17]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1111\/nbu.12542"],"URL":"https:\/\/doi.org\/10.1111\/nbu.12542","archive":["Portico"],"relation":{},"ISSN":["1471-9827","1467-3010"],"issn-type":[{"value":"1471-9827","type":"print"},{"value":"1467-3010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,17]]},"assertion":[{"value":"2021-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}