{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T20:37:27Z","timestamp":1757450247848,"version":"3.40.5"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T00:00:00Z","timestamp":1626825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurology &amp; Clinical Neurosc"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>ChAdOx1 nCoV\u201019 is an effective and well\u2010tolerated coronavirus disease 2019 (COVID\u201019) vaccine. Rare cases of serious adverse events have been reported with this vaccine. We report three patients who developed Guillain\u2010Barr\u00e9 syndrome following ChAdOx1 nCoV\u201019 vaccination, who did not have active or prior COVID\u201019 infection. The neurological illness in all patients had an onset of 11\u201013\u00a0days after the first dose of vaccine. All were characterized by sensorimotor weakness of the upper and lower limbs, with facial diplegia in one and dysautonomia in the other. Nerve conduction studies were consistent with demyelination in two and axonopathy in one. Cerebrospinal fluid analysis showed albuminocytological dissociation in two patients. All patients had moderate\u2010to\u2010severe disability. They were treated with intravenous immunoglobulin, with stabilization of the disease. Proper monitoring and prompt reporting of such cases is required to ensure safety of the vaccine.<\/jats:p>","DOI":"10.1111\/ncn3.12537","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T19:44:19Z","timestamp":1626378259000},"page":"402-405","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Guillain\u2010Barr\u00e9 syndrome following ChAdOx1 nCoV\u201019 COVID\u201019 vaccination: A case series"],"prefix":"10.1111","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3654-8428","authenticated-orcid":false,"given":"Joe","family":"James","sequence":"first","affiliation":[{"name":"Department of Neurology Government Medical College Kozhikode India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3190-4737","authenticated-orcid":false,"given":"James","family":"Jose","sequence":"additional","affiliation":[{"name":"Department of Neurology Government Medical College Kozhikode India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. Abdul","family":"Gafoor","sequence":"additional","affiliation":[{"name":"Department of Neurology Government Medical College Kozhikode India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Smita","sequence":"additional","affiliation":[{"name":"Department of Neurology Government Medical College Kozhikode India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neetha","family":"Balaram","sequence":"additional","affiliation":[{"name":"Department of Neurology Government Medical College Kozhikode India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32661-1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2104840"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.64.2.242"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2009191"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.4.1110"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)62189-8"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000011881"},{"issue":"2","key":"e_1_2_7_9_1","first-page":"e13426","article-title":"Neurological complications of COVID\u201019: guillain\u2010barre syndrome following pfizer COVID\u201019 vaccine","volume":"13","author":"Waheed S","year":"2021","journal-title":"Cureus"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-242956"}],"container-title":["Neurology and Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ncn3.12537","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ncn3.12537","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ncn3.12537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T06:48:23Z","timestamp":1693291703000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ncn3.12537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,21]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1111\/ncn3.12537"],"URL":"https:\/\/doi.org\/10.1111\/ncn3.12537","archive":["Portico"],"relation":{},"ISSN":["2049-4173","2049-4173"],"issn-type":[{"type":"print","value":"2049-4173"},{"type":"electronic","value":"2049-4173"}],"subject":[],"published":{"date-parts":[[2021,7,21]]},"assertion":[{"value":"2021-05-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}