{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:46:32Z","timestamp":1747187192801,"version":"3.40.5"},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,7,16]],"date-time":"2023-07-16T00:00:00Z","timestamp":1689465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurology &amp; Clinical Neurosc"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Gorlin\u2010Goltz syndrome (GGS) is an autosomal dominant multisystemic disease with high penetrance. Headache heralding GGS has been previously reported but without discussing potential sources. We report a patient with headache and a novel association (diastematomyelia), which helped with the diagnosis. A 46\u2010year\u2010old woman presented with persistent holocranial headache. On examination, countless hyperpigmented basal cell nevi over the face, pits over the palmar\/plantar surface, and palmar and plantar keratosis were observed. A magnetic resonance imaging (MRI) of the spinal cord revealed diastematomyelia. Diagnosis of GGS was finally made. Headache and diastematomyelia should be included in the clinical picture of GGS.<\/jats:p>","DOI":"10.1111\/ncn3.12767","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T04:24:00Z","timestamp":1689567840000},"page":"328-331","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Headache as the presenting manifestation of <scp>Gorlin\u2010Goltz<\/scp> syndrome with diastematomyelia: A case report"],"prefix":"10.1111","volume":"11","author":[{"given":"Ritwik","family":"Ghosh","sequence":"first","affiliation":[{"name":"Department of General Medicine Burdwan Medical College, and Hospital  Burdwan India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mois\u00e9s","family":"Le\u00f3n\u2010Ruiz","sequence":"additional","affiliation":[{"name":"Section of Clinical Neurophysiology, Department of Neurology University Hospital \"La Paz\"  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siktha","family":"Purkait","sequence":"additional","affiliation":[{"name":"Department of General Medicine Burdwan Medical College, and Hospital  Burdwan India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipayan","family":"Roy","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences (AIIMS)  Jodhpur India"},{"name":"Indian Institute of Technology (IIT), Madras  Chennai India"},{"name":"School of Humanities Indira Gandhi National Open University  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tapas","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of Anatomy Burdwan Medical College and Hospital  Burdwan India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1769-4809","authenticated-orcid":false,"given":"Juli\u00e1n","family":"Benito\u2010Le\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital \"12 de Octubre\"  Madrid Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED)  Madrid Spain"},{"name":"Department of Medicine Complutense University  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20700"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2017.07.018"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2017.13.4.439"},{"key":"e_1_2_10_5_1","unstructured":"WeerakkodyY.Diastematomyelia. Radiopaedia. Last revised on December 5 2021.https:\/\/radiopaedia.org\/articles\/diastematomyelia"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.257991"},{"issue":"15","key":"e_1_2_10_7_1","first-page":"365","article-title":"Odontogenic (concomitant) etiology of headache","volume":"147","author":"Lunardon M","year":"1997","journal-title":"Wien Med Wochenschr"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.22540\/JFSF-02-016"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-88-470-0651-5_38"}],"container-title":["Neurology and Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ncn3.12767","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T08:38:36Z","timestamp":1699605516000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ncn3.12767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,16]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/ncn3.12767"],"URL":"https:\/\/doi.org\/10.1111\/ncn3.12767","archive":["Portico"],"relation":{},"ISSN":["2049-4173","2049-4173"],"issn-type":[{"type":"print","value":"2049-4173"},{"type":"electronic","value":"2049-4173"}],"subject":[],"published":{"date-parts":[[2023,7,16]]},"assertion":[{"value":"2023-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}