{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T20:56:46Z","timestamp":1767992206731,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,24]],"date-time":"2014-03-24T00:00:00Z","timestamp":1395619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2014,4]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>Vascular calcification (VC<\/jats:styled-content>) is common among patients with chronic kidney disease (CKD<\/jats:styled-content>) due to the strong prevalence of cardiovascular and CKD<\/jats:styled-content>\u2010related risk factors such as diabetes mellitus (DM<\/jats:styled-content>), hypertension and phosphate retention. Kidney transplantation improves kidney function and abnormal mineral metabolism at the same time. It remains unclear whether kidney transplantation favourably impacts VC<\/jats:styled-content> in the long\u2010term.<\/jats:p><\/jats:sec>Methods<\/jats:title>The present study examined VC<\/jats:styled-content> in 132 kidney transplant (KT<\/jats:styled-content>) recipients who had been transplanted for longer than one year. The severity of VC<\/jats:styled-content> was compared to 129 CKD<\/jats:styled-content> stages 5\u20105D<\/jats:styled-content> patients on a kidney transplant (KT<\/jats:styled-content>) waiting list.<\/jats:p><\/jats:sec>Results<\/jats:title>The median KT<\/jats:styled-content> vintage was 88 months. The prevalence of VC<\/jats:styled-content> among KT<\/jats:styled-content> and CKD<\/jats:styled-content> patients were 54.5% and 62.8%, respectively, (P<\/jats:italic>\u2009=\u20090.2). There were no differences in age, gender, body mass index (BMI<\/jats:styled-content>), the prevalence of DM<\/jats:styled-content> or CVD<\/jats:styled-content> between the two groups. Among patients with calcification, a more severe degree was observed in KT<\/jats:styled-content> recipients (P<\/jats:italic>\u2009=\u20090.01). Aging, DM<\/jats:styled-content>, CVD<\/jats:styled-content> and dialysis vintage were associated with significant VC<\/jats:styled-content> in both groups. The degree of VC<\/jats:styled-content> in KT<\/jats:styled-content> recipients was more pronounced than that in CKD<\/jats:styled-content> patients among those who experienced prolonged dialysis vintage (>2 years) (P<\/jats:italic>\u2009=\u20090.04). Among KT<\/jats:styled-content> recipients, the severity of VC<\/jats:styled-content> increased with the length of time after transplantation and became more substantial after 5 years.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Long\u2010term KT<\/jats:styled-content> recipients demonstrated a more severe degree of VC<\/jats:styled-content> compared to matched CKD<\/jats:styled-content> stages 5\u20105D<\/jats:styled-content> patients. The severity of VC<\/jats:styled-content> became more pronounced among those with longer transplant vintage and was in part influenced by past dialysis experience.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12210","type":"journal-article","created":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T09:40:38Z","timestamp":1390383638000},"page":"251-256","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Vascular calcification in long\u2010term kidney transplantation"],"prefix":"10.1111","volume":"19","author":[{"given":"Kotcharat","family":"Vipattawat","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chagriya","family":"Kitiyakara","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bunyong","family":"Phakdeekitcharoen","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surasak","family":"Kantachuvesiri","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasant","family":"Sumethkul","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophon","family":"Jirasiritham","sequence":"additional","affiliation":[{"name":"Department of Surgery Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wasana","family":"Stitchantrakul","sequence":"additional","affiliation":[{"name":"Research Centre Faculty of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0326-731X","authenticated-orcid":false,"given":"Sinee","family":"Disthabanchong","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.70"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002059"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2010.05.016"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg414"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007080854"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04320709"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh217"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.04.024"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02814.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.07.019"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr558"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(97)00106-8"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01310308"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001820"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1797.2010.01420.x"},{"key":"e_1_2_6_17_1","first-page":"S1","article-title":"KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease\u2010Mineral and Bone Disorder (CKD\u2010MBD)","year":"2009","journal-title":"Kidney Int. 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