{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:32:19Z","timestamp":1761129139776},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T00:00:00Z","timestamp":1400544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>To assess the effectiveness of supine\/standing urinalysis for differential diagnosis of left renal vein entrapment syndrome (LRVES<\/jats:styled-content>) combined with or without glomerulopathy.<\/jats:p><\/jats:sec>Methods<\/jats:title>The enrolled patients with abnormal urinalysis and LRVES<\/jats:styled-content> demonstrated by Doppler sonography were guided to perform a supine\/standing urinalysis.<\/jats:p><\/jats:sec>Results<\/jats:title>Fifty\u2010two patients were enrolled. Most of them were adolescents (aged 14\u201329 years, 73.1%) and with low body mass index (BMI<\/jats:styled-content>, mean BMI<\/jats:styled-content>, 19.8\u2009\u00b1\u20092.4\u2009kg\/m2<\/jats:sup>). Seventeen cases (32.7%) manifested orthostatic urine abnormalities (OUA<\/jats:styled-content>, proteinuria and\/or haematuria show negative in supine while positive after 15\u2009min standing), two patients who had undergone renal biopsies both showed no evidence of kidney lesions, another two patients were changed from abnormal to normal urinalysis after weight gain. The remaining 35 cases (67.3%) manifested non\u2010orthostatic urine abnormalities (NOUA<\/jats:styled-content>, proteinuria and\/or haematuria show positive both in supine and standing), 15 patients had undergone renal biopsies and showed different degrees of glomerulopathy. After prednisone\/immunosuppression therapy, four patients with glomerulonephritis were changed from the NOUA<\/jats:styled-content> to the OUA<\/jats:styled-content> classification. Statistics analyses showed that serum total protein and albumin levels were significantly lower (P<\/jats:italic>\u2009=\u20090.028, 0.007, respectively) and urinary protein was significantly higher (P<\/jats:italic>\u2009=\u20090.007) in the NOUA<\/jats:styled-content> group than in the OUA<\/jats:styled-content> group.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>After the indication of LRVES<\/jats:styled-content> by ultrasound, patients with OUA<\/jats:styled-content> likely have only LRVES<\/jats:styled-content>, while patients with NOUA<\/jats:styled-content> likely also have glomerulopathy. Supine\/standing urinalysis combined with Doppler sonography can be helpful for differential diagnosis of LRVES<\/jats:styled-content> combined with or without glomerulopathy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12227","type":"journal-article","created":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T14:06:54Z","timestamp":1394719614000},"page":"332-338","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effectiveness of supine\/standing urinalysis for differential diagnosis of left renal vein entrapment syndrome combined with or without glomerulopathy"],"prefix":"10.1111","volume":"19","author":[{"given":"Meiling","family":"Jin","sequence":"first","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"},{"name":"Medical College Nankai University Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panpan","family":"Hu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Ding","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pu","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Qiu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuwen","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuansheng","family":"Xie","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangmei","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Kidney Disease Institute of Nephrology Chinese PLA General Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,20]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"507","article-title":"[\u2018Nutcracker\u2019 phenomenon of the renal vein and venous pathology of the left kidney]","volume":"55","author":"Schepper A","year":"1972","journal-title":"J. Belge Radiol."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0009922811430527"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-012-0265-2"},{"key":"e_1_2_7_5_1","first-page":"73","article-title":"[Clinical case of the month. Nutcracker syndrome in association with a painful nephrologic disease]","volume":"62","author":"Strul N","year":"2007","journal-title":"Rev. Med. Liege"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.09.051"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq444"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr299"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0909-8"},{"key":"e_1_2_7_10_1","first-page":"429","article-title":"Nutcracker syndrome: An underdiagnosed cause for hematuria?","volume":"50","author":"Hanna HE","year":"1997","journal-title":"S. D. J. Med."},{"key":"e_1_2_7_11_1","first-page":"461","article-title":"The importance of a standing position in the diagnosis of Nutcracker phenomenon by duplex sonography","volume":"28","author":"Romera\u2010Villegas A","year":"2009","journal-title":"Int. Angiol."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004670050062"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-012-0349-1"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/kisup.2012.73"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2011.01.002"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2005.06.006"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2005.05.045"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199912000-00002"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/scrt314"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1986.219"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2010.03.004"}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnep.12227","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.12227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T12:59:51Z","timestamp":1696251591000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.12227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,20]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/nep.12227"],"URL":"https:\/\/doi.org\/10.1111\/nep.12227","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"value":"1320-5358","type":"print"},{"value":"1440-1797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,20]]},"assertion":[{"value":"2014-03-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-05-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}