{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T09:16:57Z","timestamp":1763457417658},"reference-count":4,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T00:00:00Z","timestamp":1400544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cases of life\u2010threatening thromboses in pulmonary, coronary, cerebral and peripheral vessels are associated with high\u2010dose intravenous immunoglobulin (<jats:styled-content style=\"fixed-case\">IVIg<\/jats:styled-content>) therapy that is generally considered safe. We experienced a patient with a renal graft rupture that developed after high\u2010dose <jats:styled-content style=\"fixed-case\">IVIg<\/jats:styled-content> was administered for desensitization. A needle biopsy performed 4 days prior to the rupture revealed the presence of glomerular thrombosis and mesangiolysis. The ruptured nephrectomy specimen contained renal infarction around the haemorrhagic segment and arterial wall thickening with intimal fibrosis. This might have contributed to rupturing associated with small arterial and glomerular arteriolar thrombi. This is the first case of a graft rupture as a complication of high\u2010dose <jats:styled-content style=\"fixed-case\">IVIg<\/jats:styled-content> we have encountered.<\/jats:p>","DOI":"10.1111\/nep.12248","type":"journal-article","created":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T07:26:00Z","timestamp":1400570760000},"page":"35-36","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Graft rupture after high\u2010dose intravenous immunoglobulin therapy in a renal transplant patient"],"prefix":"10.1111","volume":"19","author":[{"given":"Yong\u2010Hun","family":"Sin","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Bong Seng Hospital  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong\u2010Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology Yeungnam University College of Medicine  Daegu South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joon Seok","family":"Oh","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Bong Seng Hospital  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Ho","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Bong Seng Hospital  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Bong Seng Hospital  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joong Kyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Bong Seng Hospital  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,20]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03400.x"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.08.131"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1G104"},{"key":"e_1_2_3_5_1","first-page":"294","article-title":"Adverse reactions to intravenous immunoglobulin therapy","volume":"2","author":"Iagaru N","year":"2007","journal-title":"Am. J. Clin. Med."}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnep.12248","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.12248","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T15:20:22Z","timestamp":1694445622000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.12248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,20]]},"references-count":4,"journal-issue":{"issue":"S3","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/nep.12248"],"URL":"https:\/\/doi.org\/10.1111\/nep.12248","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"value":"1320-5358","type":"print"},{"value":"1440-1797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,20]]},"assertion":[{"value":"2014-05-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}