{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:25:14Z","timestamp":1790706314534,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T00:00:00Z","timestamp":1400544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">IgA<\/jats:styled-content>nephropathy (<jats:styled-content style=\"fixed-case\">IgAN<\/jats:styled-content>) is recurrent after transplantation; however, its time of recurrence is unpredictable. To date, factors influencing<jats:styled-content style=\"fixed-case\">IgAN<\/jats:styled-content>recurrence have not been elucidated. We present a case of a 23\u2010year\u2010old man with end\u2010stage renal disease (<jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content>) who underwent living\u2010related<jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>\u2010identical pre\u2010emptive kidney transplantation (<jats:styled-content style=\"fixed-case\">PEKT<\/jats:styled-content>) using his 57\u2010year\u2010old mother as a donor.<jats:styled-content style=\"fixed-case\">IgAN<\/jats:styled-content>started when the patient was 19 years old, and renal biopsy revealed the usual pathological findings of<jats:styled-content style=\"fixed-case\">IgAN<\/jats:styled-content>. In spite of steroid therapy including steroid pulse and tonsillectomy, the patient developed nephrotic syndrome and progressed to<jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content>in 4 years. Protocol biopsy on day 19 following<jats:styled-content style=\"fixed-case\">PEKT<\/jats:styled-content>revealed active recurrent<jats:styled-content style=\"fixed-case\">IgAN<\/jats:styled-content>. Nephrotic\u2010range proteinuria and mild deterioration of kidney function developed regardless of strong immunosuppressive therapy such as steroid pulse, double filtration plasmapheresis and rituximab. We report a case of refractory<jats:styled-content style=\"fixed-case\">IgAN<\/jats:styled-content>that recurred 19 days after transplantation. This case is considered of value to elucidate factors leading to active<jats:styled-content style=\"fixed-case\">IgAN<\/jats:styled-content>recurrence.<\/jats:p>","DOI":"10.1111\/nep.12252","type":"journal-article","created":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T07:26:00Z","timestamp":1400570760000},"page":"45-48","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Early recurrence of active<scp>IgA<\/scp>nephropathy after kidney transplantation"],"prefix":"10.1111","volume":"19","author":[{"given":"Yasuhiro","family":"Otsuka","sequence":"first","affiliation":[{"name":"Department of Nephrology and Transplantation Center Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asami","family":"Takeda","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Center Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Horike","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Center Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daijyo","family":"Inaguma","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Center Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihiko","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Center Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Watarai","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Center Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunio","family":"Morozumi","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Center Japanese Red Cross Nagoya Daini Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,20]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(88)80021-0"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs472"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200101270-00011"},{"key":"e_1_2_4_5_1","first-page":"279","article-title":"Favorable outcome of renal transplantation in patients with IgA nephropathy","volume":"56","author":"Andresdottir MB","year":"2001","journal-title":"Clin. 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