{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:56:38Z","timestamp":1764996998276},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,6,16]],"date-time":"2014-06-16T00:00:00Z","timestamp":1402876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>One of the factors that may affect survival and function of kidney graft is its functional mass.<\/jats:p><\/jats:sec>Methods<\/jats:title>In a prospective study, we investigated the impact of the ratio between donor kidney weight in grams and recipient bodyweight in kilograms (DKW<\/jats:styled-content>\/RBW<\/jats:styled-content>) on creatinine clearance, inulin clearance, and proteinuria: 154 kidneys from deceased donors were weighed and the mean kidney weight was 227\u2009\u00b1\u200959\u2009g, the bodyweight of the recipients was 64\u2009\u00b1\u200919\u2009kg.<\/jats:p><\/jats:sec>Results<\/jats:title>This study showed significant lower values of modification of diet in renal disease (MDRD<\/jats:styled-content>) in patients with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio 2.5\u2009g\/kg and between 2.5 and 4.5\u2009g\/kg compared with those with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio >4.5\u2009g\/kg as well as in patients with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio <3\u2009g\/kg and between 3 and 4\u2009g\/kg compared with those with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio >4\u2009g\/kg; moreover a random coefficient model showed a different time evolution in creatinine clearance values in patients with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> \u2264\u20093\u2009g\/kg when compared with patients with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio >4\u2009g\/kg. There were significant lower values of inulin clearance in patients with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio between 2.5 and 4.5\u2009g\/kg compared with those with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio >4.5\u2009g\/kg at 12 post\u2010transplant months and a significantly greater occurrence and earlier appearance of proteinuria in the recipients with DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio <2.5\u2009g\/kg. DKW<\/jats:styled-content>\/RBW<\/jats:styled-content> ratio did not influence DGF<\/jats:styled-content> incidence and graft survival. Donor and recipient gender, number of acute rejection episodes and donor age also significantly influenced MDRD<\/jats:styled-content> values.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Measurements of graft weight as well as donor kidney and recipient body matching should be recommended as influencing renal function.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12277","type":"journal-article","created":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T09:20:47Z","timestamp":1399454447000},"page":"420-425","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Influence of allograft weight to recipient bodyweight ratio on outcome of cadaveric renal transplantation"],"prefix":"10.1111","volume":"19","author":[{"given":"Ricardo","family":"Codas","sequence":"first","affiliation":[{"name":"Department of Transplantation Edouard Herriot Hospital Lyon 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