{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T11:52:53Z","timestamp":1765885973964},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T00:00:00Z","timestamp":1437436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Contrast\u2010induced nephropathy (<jats:styled-content style=\"fixed-case\">CIN<\/jats:styled-content>) post\u2010percutaneous coronary intervention (<jats:styled-content style=\"fixed-case\">PCI<\/jats:styled-content>) is a major cause of acute kidney injury. In this study, we established a comprehensive risk score model to assess risk of <jats:styled-content style=\"fixed-case\">CIN<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">PCI<\/jats:styled-content> procedure, which could be easily used in a clinical environment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 805 <jats:styled-content style=\"fixed-case\">PCI<\/jats:styled-content> patients, divided into analysis cohort (70%) and validation cohort (30%), were enrolled retrospectively in this study. Risk factors for <jats:styled-content style=\"fixed-case\">CIN<\/jats:styled-content> were identified using univariate analysis and multivariate logistic regression in the analysis cohort. Risk score model was developed based on multiple regression coefficients. Sensitivity and specificity of the new risk score system was validated in the validation cohort. Comparisons between the new risk score model and previous reported models were applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of post\u2010<jats:styled-content style=\"fixed-case\">PCI CIN<\/jats:styled-content> in the analysis cohort (<jats:italic>n<\/jats:italic>\u2009=\u2009565) was 12%. Considerably high <jats:styled-content style=\"fixed-case\">CIN<\/jats:styled-content> incidence (50%) was observed in patients with chronic kidney disease (<jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content>). Age &gt;75, body mass index (<jats:styled-content style=\"fixed-case\">BMI)<\/jats:styled-content> &gt;25, myoglobin level, cardiac function level, hypoalbuminaemia, history of chronic kidney disease (<jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content>), Intra\u2010aortic balloon pump (<jats:styled-content style=\"fixed-case\">IABP<\/jats:styled-content>) and peripheral vascular disease (<jats:styled-content style=\"fixed-case\">PVD<\/jats:styled-content>) were identified as independent risk factors of post\u2010<jats:styled-content style=\"fixed-case\">PCI CIN<\/jats:styled-content>. A novel risk score model was established using multivariate regression coefficients, which showed highest sensitivity and specificity (0.917, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.877\u20130.957) compared with previous models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A new post\u2010<jats:styled-content style=\"fixed-case\">PCI CIN<\/jats:styled-content> risk score model was developed based on a retrospective study of 805 patients. Application of this model might be helpful to predict <jats:styled-content style=\"fixed-case\">CIN<\/jats:styled-content> in patients undergoing <jats:styled-content style=\"fixed-case\">PCI<\/jats:styled-content> procedure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12429","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T11:18:44Z","timestamp":1424690324000},"page":"544-551","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Novel risk score of contrast\u2010induced nephropathy after percutaneous coronary intervention"],"prefix":"10.1111","volume":"20","author":[{"given":"Ling","family":"Ji","sequence":"first","affiliation":[{"name":"West China Medical School of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XiaoFeng","family":"Su","sequence":"additional","affiliation":[{"name":"West China Medical School of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Qin","sequence":"additional","affiliation":[{"name":"Division of Nephrology West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XuHua","family":"Mi","sequence":"additional","affiliation":[{"name":"Division of Nephrology West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Nephrology West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XiaoHong","family":"Tang","sequence":"additional","affiliation":[{"name":"Division of Nephrology West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Nephrology West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LiChuan","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Nephrology West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1954.tb18632.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/26964464"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00150-2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00917-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.10.018"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.068"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.03.008"},{"key":"e_1_2_7_9_1","first-page":"240","article-title":"Risk score for contrast induced nephropathy following percutaneous coronary intervention","volume":"20","author":"Ghani AA","year":"2009","journal-title":"Saudi J. 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