{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T03:28:20Z","timestamp":1775791700916,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,12,23]],"date-time":"2015-12-23T00:00:00Z","timestamp":1450828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>There is a paucity of data pertaining to the incidence of biopsy\u2010proven glomerulonephritis (<jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content>) in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia. This retrospective study aims to review the data from all adult native renal biopsies performed in the state of <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>ueensland from 2002 to 2011 \u2013 comparing results with centres from across the world.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pathology reports of 3697 adult native kidney biopsies were reviewed, of which 2048 had <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> diagnoses. Age, gender, clinical indication and histopathology findings were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age at biopsy was 48\u2009\u00b1\u200917 years. Male preponderance was noted overall (\u223c60%), with lupus nephritis being the only individual <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> with female predilection. The average rate of biopsy was 12.04 per hundred thousand people per year (php\/yr). Nephrotic and nephritic syndromes comprised approximately 75% of all clinical indications that lead to <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> diagnoses. <jats:styled-content style=\"fixed-case\">IgA<\/jats:styled-content> nephropathy (1.41 php\/yr) was the most common primary <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> followed by focal segmental glomerulosclerosis (1.02 php\/yr) and crescentic <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> (0.73 php\/yr). Diabetic nephropathy (0.84 php\/yr), lupus nephritis (0.69 php\/yr) and amyloidosis (0.19 php\/yr) were the most commonly identified secondary <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">IgA<\/jats:styled-content> nephropathy is the predominant primary <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>ueensland, and nephrotic syndrome the most common indication for a renal biopsy. While crescentic <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> incidence has significantly increased with time, focal segmental glomerulosclerosis incidence has not shown any trend. Incidence of <jats:styled-content style=\"fixed-case\">GN<\/jats:styled-content> overall appears to increase with age. The annual rate of biopsy in this study appears lower than previously published in an <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralian population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12559","type":"journal-article","created":{"date-parts":[[2015,7,8]],"date-time":"2015-07-08T06:16:11Z","timestamp":1436336171000},"page":"28-34","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Epidemiology of biopsy\u2010proven glomerulonephritis in <scp>Q<\/scp>ueensland adults"],"prefix":"10.1111","volume":"21","author":[{"given":"Dev","family":"Jegatheesan","sequence":"first","affiliation":[{"name":"Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"},{"name":"School of Medicine The University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karthik","family":"Nath","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Queensland  Brisbane Queensland Australia"},{"name":"Princess Alexandra Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Reyaldeen","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Queensland  Brisbane Queensland Australia"},{"name":"Princess Alexandra Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goutham","family":"Sivasuthan","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George T","family":"John","sequence":"additional","affiliation":[{"name":"Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo","family":"Francis","sequence":"additional","affiliation":[{"name":"Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohana","family":"Rajmokan","sequence":"additional","affiliation":[{"name":"Communicable Diseases Unit Department of Health Queensland Government  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dwarakanathan","family":"Ranganathan","sequence":"additional","affiliation":[{"name":"Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp091"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs437"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/12.3.418"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi207"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfl237"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn564"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh521"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-012-0746-8"},{"key":"e_1_2_6_10_1","unstructured":"Estimated resident population by single year \u2013 ages sex and state Australia 2002\u20132011 [Intranet].2015. 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