{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T23:35:23Z","timestamp":1772753723845,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,21]],"date-time":"2016-01-21T00:00:00Z","timestamp":1453334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>We evaluated whether parathyroidectomy (PTX<\/jats:styled-content>) was associated with survival of dialysis patients.<\/jats:p><\/jats:sec>Methods<\/jats:title>In a cohort study with one year follow\u2010up, data from 146 haemodialysis patients from a hospital were analyzed. We compared the baseline data between patients receiving PTX<\/jats:styled-content> surgery and those who had not undergone PTX<\/jats:styled-content>. The C<\/jats:styled-content>ox proportional hazards regression was used to examine the effect of PTX<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>Patients who had received PTX<\/jats:styled-content> surgery were more likely to be older, have longer duration of dialysis, higher ultrafiltration rate, C\u2010reactive protein (CRP<\/jats:styled-content>), alkaline phosphatase (ALP<\/jats:styled-content>), and lower albumin compared with those who had not receive PTX<\/jats:styled-content>. During 1 year follow\u2010up, 21 (17.1%) patients died, of whom seven died from cerebrovascular events, 10 died from cardiovascular disease, and four died from infection. The mortality was 9.4% in the PTX<\/jats:styled-content> group and 17.3% in the control group. The PTX<\/jats:styled-content> group had a significantly lower risk of all\u2010cause mortality than the control group (P<\/jats:italic>\u2009=\u20090.005). There was a significantly lower risk of all\u2010cause mortality in the PTX<\/jats:styled-content> group compared with the non\u2010PTX<\/jats:styled-content> group (HR<\/jats:styled-content>\u2009=\u20090.93, 95%CI<\/jats:styled-content>: 0.89\u20130.97). The lower risk (HR<\/jats:styled-content>\u2009=\u20090.92, 95%CI<\/jats:styled-content>: 0.85\u20130.98) of PTX<\/jats:styled-content> group was not changed after adjusting potential factors. Our results also suggested that this relationship was independent of many potential confounding factors.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Parathyroidectomy was related to significant reduction in all\u2010cause among patients with severe SHPT<\/jats:styled-content>. PTX<\/jats:styled-content> may be considered as a matter of priority, from which dialysis patients would benefit.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12564","type":"journal-article","created":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T04:39:07Z","timestamp":1437453547000},"page":"133-138","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Impact of parathyroidectomy on survival among haemodialysis patients: A prospective cohort study"],"prefix":"10.1111","volume":"21","author":[{"given":"Weidong","family":"Li","sequence":"first","affiliation":[{"name":"Department of Thyroid Breast Surgery Cangzhou People's Hospital Cangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manli","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thyroid Breast Surgery Cangzhou People's Hospital Cangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shutong","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Nephrology Cangzhou People's Hospital Cangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjie","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Thyroid Breast Surgery Cangzhou People's Hospital Cangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianfeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Hebei General Hospital Shijiazhuang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nephrology China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Yao","sequence":"additional","affiliation":[{"name":"Endoscopy Center China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.09802.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60952-6"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084943"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.10.009"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000100127.54107.57"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2008.03.020"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000133041.27682.A2"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116720"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.81.4.1598"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-14-100"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1205624"},{"key":"e_1_2_6_13_1","first-page":"S1","article-title":"KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease\u2010Mineral and Bone Disorder (CKD\u2010MBD)","volume":"113","author":"Kidney Disease: Improving Global Outcomes (KDIGO) CKDMBD Work Group","year":"2009","journal-title":"Kidney Int. 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