{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T19:17:41Z","timestamp":1785266261106,"version":"3.55.0"},"reference-count":41,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,11,11]],"date-time":"2016-11-11T00:00:00Z","timestamp":1478822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to determine the incidence and risk factors of acute kidney injury (AKI) following transcatheter aortic valve replacement (TAVR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included all adult patients undergoing TAVR for aortic stenosis from 1 January 2008 to 30 June 2014 at a tertiary referral hospital. AKI was defined based on Kidney Disease: Improving Global Outcomes criteria. We performed a multivariate logistic regression to identify factors associated with post\u2010procedural AKI occurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three hundred eighty\u2010six patients met the inclusion criteria, of which 106 (28%) developed AKI. In multivariate analysis, AKI development was independently associated with a transapical approach (odds ratio (OR), 2.81; 95% confidence interval (CI), 1.72\u20134.65 compared with transfemoral approach) and the need for an intra\u2010aortic balloon pump (OR, 9.11; 95% CI, 1.77\u201368.29). Higher baseline renal function (OR, 0.78 per 10\u2009mL\/min per 1.73\u2009m<jats:sup>2<\/jats:sup> increment in glomerular filtration rate; 95% CI, 0.68\u20130.87) was significantly associated with a decreased risk of AKI. After adjustment for the Society of Thoracic Surgeons' risk score, post\u2010procedural AKI development remained significantly associated with an increased in\u2010hospital (OR, 4.74; 95% CI, 1.39\u201318.48) and 6\u2010month mortality (OR, 4.66; 95% CI, 2.32\u20139.63).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a cohort of patients undergoing TAVR for aortic stenosis, AKI commonly occurred and was significantly associated with increased mortality. Baseline renal function, procedure approach and the need for circulatory support were important predictive factors for post\u2010procedural AKI occurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12704","type":"journal-article","created":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T18:58:38Z","timestamp":1451415518000},"page":"1041-1046","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Incidence and risk factors of acute kidney injury following transcatheter aortic valve replacement"],"prefix":"10.1111","volume":"21","author":[{"given":"Charat","family":"Thongprayoon","sequence":"first","affiliation":[{"name":"Division of Nephrology and Hypertension Department of Medicine Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wisit","family":"Cheungpasitporn","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension Department 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