{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T13:28:54Z","timestamp":1747661334556},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T00:00:00Z","timestamp":1482364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Royal Free Hampstead NHS Trust"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Encapsulating peritoneal sclerosis (EPS) is a rare but potentially devastating complication of long\u2010term peritoneal dialysis (PD). Changes to the peritoneal membrane occur with duration of PD therapy. To determine the potential effect of prospective computerized tomography (CT) scanning, we reviewed the scans of patients who had developed EPS compared with those without EPS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively compared CT scans that had been prospectively performed in a screening program for PD patients after 4\u2009years of PD and compared scans from 18 patients with confirmed EPS and 26 vintage matched controls without EPS. Anonymized scans were reported independently by two blinded experienced radiologists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Peritoneal thickening, calcification, bowel tethering, thickening and dilatation were significantly more commonly reported in the EPS group. Total combined radiological scores, also including septation within peritoneal fluid, were significantly higher in the EPS group and the greatest for those who died as a consequence of EPS. Simplified scoring based on presence or absence, then for a score of \u22653.0, gave a receiver operating characteristic value of 0.87 for EPS, with a sensitivity of 78% and specificity of 85%, respectively. Inter\u2010observer agreement varied from poor to good, being the greatest for calcification and bowel dilatation and the lowest for peritoneal thickening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CT scan reporting can differentiate EPS from peritoneal changes associated with duration of PD therapy. Severity of abnormalities was associated with clinical outcomes. However, inter\u2010observer agreement varies with different radiological appearances, and future studies are required to determine weighting of radiological changes to provide prognostic information for clinicians and patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12718","type":"journal-article","created":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T00:28:15Z","timestamp":1452040095000},"page":"19-24","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Can radiological assessment of abdominal computerized scans diagnose encapsulating peritoneal sclerosis in long\u2010term peritoneal dialysis patients?"],"prefix":"10.1111","volume":"22","author":[{"given":"Sam","family":"Stuart","sequence":"first","affiliation":[{"name":"Department of Radiology Royal Free Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Stott","sequence":"additional","affiliation":[{"name":"Faculty of Health and Human Sciences University of Hertfordshire  Hatfield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antony","family":"Goode","sequence":"additional","affiliation":[{"name":"Department of Radiology Royal Free Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte J","family":"Cash","sequence":"additional","affiliation":[{"name":"Department of Radiology Royal Free Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Davenport","sequence":"additional","affiliation":[{"name":"UCL Center for Nephrology Royal Free Hospital, University College London Medical School  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1177\/089686080902900314","article-title":"Peritonitis remains the major clinical complication of peritoneal dialysis: The London, UK, peritonitis audit 2002\u20102003","volume":"29","author":"Davenport A","year":"2009","journal-title":"Perit. 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