{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T16:19:45Z","timestamp":1784996385389,"version":"3.55.0"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,4,4]],"date-time":"2017-04-04T00:00:00Z","timestamp":1491264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Natural Science Foundation of Shandong Province, China","award":["No. ZR2010HL012"],"award-info":[{"award-number":["No. ZR2010HL012"]}]},{"name":"Science and Technology Development Program of Shandong Province, China","award":["No. 2012YD18079"],"award-info":[{"award-number":["No. 2012YD18079"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Total parathyroidectomy with autotransplantation (TPTX\u2009+\u2009AT) and subtotal parathyroidectomy (SPTX) have been recommended to patients with renal hyperparathyroidism (RHPT).But which one is the best surgical method remains controversial. The aim of the present study was to compare the two surgical procedures with respect to long\u2010term outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A literature search was undertaken using Medline, EMBASE, CNKI and CBM from inception to May 2015. Study quality was assessed using the Newcastle\u2010Ottawa Scale. Data were analyzed using Review Manager version 5.1.0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 13 studies comprising 1589 patients with renal failure were identified. There was no statistically significant difference in the rate of symptomatic improvement (OR 0.77; 95%CI 0.22 to 2.69; <jats:italic>P =<\/jats:italic> 0.68), radiological success (OR 0.17; 95%CI 0.02 to 1.56; <jats:italic>P =<\/jats:italic> 0.90), hyperparathyroidism recurrence or persistence (OR 1.31; 95%CI 0.65 to 2.65; <jats:italic>P =<\/jats:italic> 0.45) and reoperation (OR 1.55; 95%CI 0.62 to 3.86; <jats:italic>P =<\/jats:italic> 0.35) between TPTX\u2009+\u2009AT and SPTX. The effects on serum calcium and parathyroid hormone (PTH) were similar between two surgical protocols.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both the TPTX\u2009+\u2009AT and SPTX were effective in treating RHPT and preventing recurrence. The difference between the two surgeries in recurrence or persistence and reoperation rate was insignificant. Further prospective, randomized controlled trials with high statistic power are necessary to comparative the two surgeries on the long term safety.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.12801","type":"journal-article","created":{"date-parts":[[2016,4,16]],"date-time":"2016-04-16T15:12:41Z","timestamp":1460819561000},"page":"388-396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Total parathyroidectomy with autotransplantation versus subtotal parathyroidectomy for renal hyperparathyroidism: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"22","author":[{"given":"Juan","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Nephrology Affiliated Qianfoshan Hospital of Shandong University  No. 16766 Jingshi Road Jinan 250014 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Nephrology Affiliated Qianfoshan Hospital of Shandong University  No. 16766 Jingshi Road Jinan 250014 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianglei","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Nephrology Affiliated Qianfoshan Hospital of Shandong University  No. 16766 Jingshi Road Jinan 250014 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zunsong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nephrology Affiliated Qianfoshan Hospital of Shandong University  No. 16766 Jingshi Road Jinan 250014 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiyu","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Nephrology Affiliated Qianfoshan Hospital of Shandong University  No. 16766 Jingshi Road Jinan 250014 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Nephrology Affiliated Qianfoshan Hospital of Shandong University  No. 16766 Jingshi Road Jinan 250014 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh1049"},{"key":"e_1_2_8_3_1","first-page":"1","article-title":"Clinical practice guidelines for the prevention, diagnosis, evaluation and treatment of mineral and bone disorders in chronic kidney disease (CKD\u2010MBD) in adults","volume":"33","author":"Bellorin\u2010Font E","year":"2013","journal-title":"Nefrologia"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.67139.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001436"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2015.72"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-009-9943-3"},{"key":"e_1_2_8_8_1","first-page":"S1","article-title":"Improving Global Outcomes CKDMBDWG. 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