{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T19:30:23Z","timestamp":1768678223630,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T00:00:00Z","timestamp":1530489600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Herein, we report a case of antibody\u2010mediated rejection (ABMR) due to anti\u2010HLA\u2010DQ antibody after pregnancy and delivery in a female kidney transplant recipient. A 34\u2010year\u2010old female recipient was admitted at 2 years after delivery for an examination of an elevated serum creatinine (S\u2010Cr) level. The patient had received a living kidney transplantation from her mother at 22 years of age, and her kidney graft function was almost stable. The episode biopsy showed peritubular capillaritis and transplant capillaropathy with C4d immunoreactivity in the peritubular capillaries. Additional examination revealed expression of a donor\u2010specific antibody (DSA) against HLA\u2010DQ5, leading to the diagnosis of chronic active ABMR. Intravenous immunoglobulin, plasma exchange, and rituximab were administered, and her S\u2010Cr level was maintained stable. This case demonstrates a possible relationship between pregnancy\/delivery and development of ABMR due to a <jats:italic>de novo<\/jats:italic> DSA in a female kidney transplant recipient.<\/jats:p>","DOI":"10.1111\/nep.13279","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T05:00:51Z","timestamp":1530594051000},"page":"81-84","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Antibody\u2010mediated rejection due to anti\u2010HLA\u2010DQ antibody after pregnancy and delivery in a female kidney transplant recipient"],"prefix":"10.1111","volume":"23","author":[{"given":"Makoto","family":"Sagasaki","sequence":"first","affiliation":[{"name":"Division of Nephrology and Hypertension, Department of Internal Medicine The Jikei University School of Medicine  Tokyo 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