{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T09:27:52Z","timestamp":1777973272765,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T00:00:00Z","timestamp":1555459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Our aim was threefold: first, to determine the incidence of active TB in our cohort, second to investigate the risk factors for active TB and third, to understand current screening practices. The ultimate goal was to use our findings to inform development of local and national guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The records of all adult patients who underwent renal transplantation at our centre from 2005 to 2014 were retrospectively reviewed to assess current screening practices, the risks for and burden of active TB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 660 individuals underwent renal transplantation during this period, totalling 3647 person years of follow up. Two patients were diagnosed with active TB after renal transplant, resulting in an incidence of 55 per 100\u2009000 person\u2010years. Of 656 transplant recipients, 102 (15.5%) were born in high TB incidence countries and 89 (13.5%) had an interferon gamma release assay (IGRA) at any point. Individuals born in high TB risk countries had a much higher incidence of active TB (353 per 100\u2009000 person\u2010years). Ten individuals had positive IGRA tests, of whom two were treated for active TB, two received chemoprophylaxis and six were not treated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the absence of formal guidelines, IGRA\u2010based screening for LTBI was infrequently performed. Our data suggest that screening and treatment of renal transplant recipients born in high incidence countries is an important preventive measure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.13386","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T16:15:40Z","timestamp":1523895340000},"page":"569-574","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Mycobacterium tuberculosis:<scp>A<\/scp>ctive disease and latent infection in a renal transplant cohort"],"prefix":"10.1111","volume":"24","author":[{"given":"Nastaran","family":"Rafiei","sequence":"first","affiliation":[{"name":"Monash Infectious Diseases Monash Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackie","family":"Williams","sequence":"additional","affiliation":[{"name":"Monash Infectious Diseases Monash Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William R","family":"Mulley","sequence":"additional","affiliation":[{"name":"Department of Nephrology Monash Medical Centre Melbourne Victoria Australia"},{"name":"Department of Medicine, Centre for Inflammatory Diseases Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M","family":"Trauer","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grant A","family":"Jenkin","sequence":"additional","affiliation":[{"name":"Monash Infectious Diseases Monash Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin A","family":"Rogers","sequence":"additional","affiliation":[{"name":"Monash Infectious Diseases Monash Health Melbourne Victoria Australia"},{"name":"Department of Medicine, Centre for Inflammatory Diseases Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002152"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70069-X"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"E217","DOI":"10.33321\/cdi.2015.39.21","article-title":"Tuberculosis notifications in Australia, 2012 and 2013","volume":"39","author":"Toms C","year":"2015","journal-title":"Commun Dis Intell Q Rep"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1005750"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/514993"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000183552"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001224"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12100"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00000712"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12641"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1086\/597590"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp021045"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01245-2015"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/nep.12068"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.144295"},{"key":"e_1_2_7_17_1","unstructured":"World Health Organization. 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