{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T12:01:54Z","timestamp":1768996914297,"version":"3.49.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Acute kidney injury (AKI) is a known complication of patients undergoing cardiac catheterization or percutaneous coronary interventions (PCI).The Mehran score was developed to identify patients at risk for AKI after cardiac catheterization or PCI, but its use of contrast volume as part of the score calculation limits its application prior to the procedure. In this study, we evaluated the utility of a modified Mehran score that utilizes only pre\u2010procedural data by excluding contrast volume.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was done in a retrospective fashion using data from patients who received PCI at our institution between July 2015 and December 2017 by evaluating the discriminative ability of the scoring systems for predicting outcomes through a receiver\u2010operator characteristic curve analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One thousand five hundred and seven patients were included in the study. A total of 70 (4.6%) patients developed AKI. The removal of contrast volume from the Mehran score resulted in a small loss of discrimination with AUROC 0.73 vs 0.74, <jats:italic>P<\/jats:italic> = .01 for the pre\u2010procedural Mehran and the original Mehran, respectively. When compared to the original score, the pre\u2010procedural Mehran score had a four\u2010category net discrimination index (NRI) of \u20110.10 and an integrated discrimination index (IDI) for of \u22120.12.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite a small loss in discrimination, there was no difference in the four\u2010category net discrimination index between the two scores. The pre\u2010procedural modified Mehran score is a useful clinical predictor of the risk of AKI in patients undergoing PCI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nep.13769","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T19:49:12Z","timestamp":1598557752000},"page":"23-29","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Performance of a <scp>pre\u2010procedural<\/scp> Mehran score to predict acute kidney injury after percutaneous coronary intervention"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9843-7013","authenticated-orcid":false,"given":"Anamarys","family":"Blanco","sequence":"first","affiliation":[{"name":"GME department University of Central Florida College of Medicine  Orlando Florida USA"},{"name":"Ocala Regional Medical Center Internal Medicine Residency Program  Ocala Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal","family":"Rahim","sequence":"additional","affiliation":[{"name":"GME department University of Central Florida College of Medicine  Orlando Florida USA"},{"name":"Ocala Regional Medical Center Internal Medicine Residency Program  Ocala Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Nguyen","sequence":"additional","affiliation":[{"name":"GME department University of Central Florida College of Medicine  Orlando Florida USA"},{"name":"Ocala Regional Medical Center Internal Medicine Residency Program  Ocala Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Quach","sequence":"additional","affiliation":[{"name":"GME department University of Central Florida College of Medicine  Orlando Florida USA"},{"name":"Ocala Regional Medical Center Internal Medicine Residency Program  Ocala Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sai","family":"Guduru","sequence":"additional","affiliation":[{"name":"GME department University of Central Florida College of Medicine  Orlando Florida USA"},{"name":"Ocala Regional Medical Center Internal Medicine Residency Program  Ocala Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shraddha","family":"Makadia","sequence":"additional","affiliation":[{"name":"GME department University of Central Florida College of Medicine  Orlando Florida USA"},{"name":"Ocala Regional Medical Center Internal Medicine Residency Program  Ocala Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8842-7233","authenticated-orcid":false,"given":"Khalid","family":"Abusaada","sequence":"additional","affiliation":[{"name":"GME department University of Central Florida College of Medicine  Orlando Florida USA"},{"name":"Ocala Regional Medical Center Internal Medicine Residency Program  Ocala Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31828124ad"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjqs-2011-000041"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.109.910638"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2004090740"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.112.974493"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2017.07.482"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03530430033035"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000016043.87291.33"},{"key":"e_1_2_8_10_1","volume-title":"Safe Practices for Better Healthcare 2006 Update: A Consensus Report","author":"National Quality Forum","year":"2007"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc11455"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.068"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01372-9"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_8_15_1","volume-title":"Nutritional Anaemias: Report of a WHO Scientific Group [Meeting Held in Geneva from 13 to 17 March, 1967]","author":"WHO Scientific Group on Nutritional Anaemias & World Health Organization","year":"1968"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2929"},{"key":"e_1_2_8_18_1","first-page":"h4935","article-title":"Risk prediction models for contrast induced nephropathy: systematic review","volume":"351","author":"Silver SA","year":"2015","journal-title":"BMJ"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2015.05.007"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.10.007"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25109"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003319712467224"},{"key":"e_1_2_8_23_1","first-page":"240","article-title":"Risk score for contrast induced nephropathy following percutaneous coronary intervention","volume":"20","author":"Ghani AA","year":"2009","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.03.026"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-014-0942-9"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0b013e328335227c"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.05.079"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.11.133"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2014.05.025"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1159\/000443936"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2014.12.016"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpradiol.2016.02.001"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.4037\/ccn2011746"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.22060"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.955310"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2017.08.018"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.218677"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.06.016"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.02.086"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.114.000903"}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.13769","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nep.13769","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.13769","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T08:40:52Z","timestamp":1693816852000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.13769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,9]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/nep.13769"],"URL":"https:\/\/doi.org\/10.1111\/nep.13769","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"value":"1320-5358","type":"print"},{"value":"1440-1797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,9]]},"assertion":[{"value":"2020-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}