{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T12:58:33Z","timestamp":1755694713996,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T00:00:00Z","timestamp":1601856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of acute interstitial nephritis with associated nephrogenic diabetes insipidus in a patient treated with temozolomide and sulfamethoxazole\u2010trimethoprim for glioblastoma multiforme. Kidney biopsy demonstrated focal tubulointerstitial change with tubular dilatation, epithelial change and interstitial inflammation. The patient's kidney function improved with cessation of sulfamethoxazole\u2010trimethoprim and treatment with hydrochlorothiazide for nephrogenic diabetes insipidus. Recommencement of temozolomide did not result in further deterioration in kidney function. In this case report, we discuss the novel association between sulfamethoxazole\u2010trimethoprim\u2010induced acute interstitial nephritis and nephrogenic diabetes insipidus, and suggest possible mechanisms involved.<\/jats:p>","DOI":"10.1111\/nep.13783","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T06:24:35Z","timestamp":1601965475000},"page":"12-14","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Acute interstitial nephritis and nephrogenic diabetes insipidus following treatment with sulfamethoxazole\u2010trimethoprim and temozolomide"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1649-8101","authenticated-orcid":false,"given":"Akshay","family":"Athavale","sequence":"first","affiliation":[{"name":"Department of Renal Medicine Concord Repatriation General Hospital  Concord New South Wales Australia"},{"name":"Concord Clinical School, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism Concord Repatriation General Hospital  Concord New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meg","family":"Jardine","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Concord Repatriation General Hospital  Concord New South Wales Australia"},{"name":"Concord Clinical School, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"},{"name":"Renal and Metabolic Division The George Institute for Global Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Concord Repatriation General Hospital  Concord New South Wales Australia"},{"name":"Concord Clinical School, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"},{"name":"Renal and Metabolic Division The George Institute for Global Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaundeep","family":"Sen","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Concord Repatriation General Hospital  Concord New South Wales Australia"},{"name":"Concord Clinical School, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8164-8786","authenticated-orcid":false,"given":"Angus","family":"Ritchie","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Concord Repatriation General Hospital  Concord New South Wales Australia"},{"name":"Concord Clinical School, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0367-6677","authenticated-orcid":false,"given":"Amanda Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Concord Repatriation General Hospital  Concord New South Wales Australia"},{"name":"Concord Clinical School, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"},{"name":"Renal and Metabolic Division The George Institute for Global Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000654"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpneph0076"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01390118"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1803760"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(89)80074-5"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2010.501930"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks030"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.5414\/CN10838"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.5414\/CN109163"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07630717"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.5414\/CNP72331"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfu326"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2016.11.004"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S120662"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.02780312"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2010.09.005"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.172273"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.13991"}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.13783","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nep.13783","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.13783","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T08:41:30Z","timestamp":1693816890000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.13783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,5]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/nep.13783"],"URL":"https:\/\/doi.org\/10.1111\/nep.13783","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"type":"print","value":"1320-5358"},{"type":"electronic","value":"1440-1797"}],"subject":[],"published":{"date-parts":[[2020,10,5]]},"assertion":[{"value":"2020-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}