{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T03:04:27Z","timestamp":1783825467632,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Acute interstitial nephritis can result due to exposure to any medication, toxins, infections or malignancy. In the midst of this Coronavirus (COVID\u201019) pandemic, there has been a race for finding remedies to prevent the spread of and control the complications due to Severe Acute Respiratory Syndrome Coronavirus 2. Certain Indian medicinal herb concoctions like kabasura kudineer and nilavembu kudineer are being widely publicized to boost immunity and reduce the risk of developing COVID\u201019. Little knowledge exists about the adverse effects of these herbal remedies. We report two patients who presented to us with vague complaints following the ingestion of kabasura kudineer and we diagnosed them with acute tubulointerstitial nephritis (ATIN). The temporal relationship of ingestion of these remedies to the development of ATIN calls for vigilance and caution with regular monitoring of renal functions especially in those with chronic kidney disease.<\/jats:p>","DOI":"10.1111\/nep.13947","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T03:46:35Z","timestamp":1627530395000},"page":"961-964","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Traditional medicines prescribed for prevention of <scp>COVID<\/scp>\u201019: Use with caution"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2983-4554","authenticated-orcid":false,"given":"Rajeevalochana","family":"Parthasarathy","sequence":"first","affiliation":[{"name":"Department of Nephrology The Madras Medical Mission  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milly","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Nephrology The Madras Medical Mission  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Koshy","sequence":"additional","affiliation":[{"name":"Department of Pathology The Madras Medical Mission  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhusri","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Nephrology The Madras Medical Mission  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgi","family":"Abraham","sequence":"additional","affiliation":[{"name":"Department of Nephrology The Madras Medical Mission  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"S0975\u20109476(20)3","article-title":"In silico computational screening of kabasura kudineer\u2014official siddha formulation and JACOM against SARS\u2010CoV\u20102 spike protein","author":"Kiran G","year":"2020","journal-title":"J Ayurveda Integr Med"},{"key":"e_1_2_4_3_1","volume-title":"Deaths: Leading Causes for 2017","author":"Heron M","year":"2019"},{"key":"e_1_2_4_4_1","unstructured":"National Kidney Foundation website\u2014Kidney Disease\u2014A to Z Health Guide\u2014Use of Herbal Supplements in Chronic Kidney Disease.http:\/\/www.kidney.org\/ATOZ\/."},{"key":"e_1_2_4_5_1","first-page":"970","article-title":"Drug\u2010induced kidney disease","volume":"51","author":"Singh N","year":"2003","journal-title":"J Assoc Phys India"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2019.08.003"},{"issue":"2","key":"e_1_2_4_7_1","first-page":"9992e7","article-title":"Anti\u2010inflammatory, antipyretic and antibacterial study of kabasura kudineer choornam","volume":"7","author":"Saravanan J","year":"2018","journal-title":"Int J Curr Adv Res"},{"issue":"5","key":"e_1_2_4_8_1","first-page":"376","article-title":"A review on \u201ckapasura kudineer\u201d\u2014a siddha formulary prediction for swine flu","volume":"7","author":"Thillaivanan S","year":"2015","journal-title":"Int J Pharm Sci Drug Res"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.138277"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/096032719101000410"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.krcp.2016.05.003"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/nep.12172"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.3339\/chikd.2015.19.2.171"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.13947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nep.13947","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.13947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T04:36:09Z","timestamp":1693197369000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.13947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,28]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1111\/nep.13947"],"URL":"https:\/\/doi.org\/10.1111\/nep.13947","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"value":"1320-5358","type":"print"},{"value":"1440-1797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,28]]},"assertion":[{"value":"2020-12-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}