{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:45:48Z","timestamp":1747187148744,"version":"3.40.5"},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T00:00:00Z","timestamp":1684886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A male aged in his mid\u201060s was diagnosed with xanthogranulomatous pyelonephritis after a left nephrectomy for a renal mass that was detected during the investigation of weight loss and drenching night sweats. Past medical history includes type 2 diabetes mellitus, transient ischaemic attack, hypertension, non\u2010alcoholic fatty liver disease, dyslipidaemia, osteoarthritis and active smoking. Three years after the initial diagnosis, the patient represented with abdominal pain. CT imaging demonstrated new pulmonary and pancreatic lesions, which were histologically confirmed to be xanthogranulomatous disease. The patient was too unstable for surgical intervention so was commenced on glucocorticoids with marked improvement in his clinical condition with resolution of inflammatory markers and radiographic improvement. Weaning of prednisolone led to a relapse of disease, which was managed with re\u2010introduction of high\u2010dose prednisolone and the initiation of azathioprine. The patient is now 2\u2009years post initiation of immunosuppressive therapy with stable renal function and no active inflammation.<\/jats:p>","DOI":"10.1111\/nep.14188","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T08:14:17Z","timestamp":1684916057000},"page":"506-509","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Metastatic xanthogranulomatous pyelonephritis managed with immunosuppression"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8190-3663","authenticated-orcid":false,"given":"Julian","family":"Daniell","sequence":"first","affiliation":[{"name":"Royal Melbourne Hospital  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugenia","family":"Pedagogos","sequence":"additional","affiliation":[{"name":"Western Health Nephrology  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anastasia","family":"Chrysostomou","sequence":"additional","affiliation":[{"name":"Epworth Health Nephrology  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,24]]},"reference":[{"issue":"8","key":"e_1_2_4_2_1","first-page":"495","article-title":"Xanthogranulomatous pyelonephritis in adults: clinical, biological, radiological and therapeutic main findings in diffuse and focal forms. About 42 cases","volume":"96","author":"Ichaoui H","year":"2018","journal-title":"Tunis Med"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.5334\/jbsr.1807"},{"volume-title":"StatPearls [Internet]","year":"2021","author":"Jha SK","key":"e_1_2_4_4_1"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1726\u20104901(08)70128\u2010X"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm458"},{"issue":"6","key":"e_1_2_4_7_1","first-page":"317","article-title":"Xanthogranulomat\u00f6se pyelonephritis mit septischen Lungenmetastasen und infiltration des Kolons. Schwierige pr\u00e4operative Differentialdiagnose zum pulmonal metastasierten Hypernephrom [Xanthogranulomatous pyelonephritis with septic lung metastases and infiltration of the colon. Difficult preoperative differential pulmonary hypernephroma metastasis diagnosis]","volume":"7","author":"Hortling N","year":"1997","journal-title":"Aktuelle Radiol."},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_213_17"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_50_18"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198903000-00008"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1976.01630250015004"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755\u20103768.2009.01726"}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.14188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T13:53:09Z","timestamp":1692280389000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.14188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,24]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/nep.14188"],"URL":"https:\/\/doi.org\/10.1111\/nep.14188","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"type":"print","value":"1320-5358"},{"type":"electronic","value":"1440-1797"}],"subject":[],"published":{"date-parts":[[2023,5,24]]},"assertion":[{"value":"2023-02-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}