{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:46:00Z","timestamp":1747187160338,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dialysis associated reactions presenting with urticarial vasculitis is rarely reported in medical literature. We report a 61\u2010year\u2010old gentleman who developed sudden onset dyspnea with diffuse erythema within 20\u2009min of haemodialysis. Patient was started on Azilsartan 3\u2009days prior to this clinical event. Labs revealed features of hemolysis and urine was positive for hemoglobinuria. All dialysis related factors responsible for this reaction were ruled out. Due to non\u2010resolution of skin rash, skin biopsy was attempted which revealed fibrinoid necrosis of occasional vessels with predominant lymphocytic infiltration suggestive of drug induced urticarial vasculitis. Complement levels were normal. He was managed with steroids, anti\u2010histaminic, discontinuation of azilsartan and change of dialyzer membrane. This case highlights a rare dermatological presentation of Type A dialysis associated reaction involving azilsartan with differential diagnosis and treatment strategies.<\/jats:p>","DOI":"10.1111\/nep.14267","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T04:35:16Z","timestamp":1704342916000},"page":"235-238","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A rare case of dialysis associated reaction presenting with urticarial vasculitis and haemoglobinuria"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6886-9015","authenticated-orcid":false,"given":"Varadharajan","family":"Jayaprakash","sequence":"first","affiliation":[{"name":"Department of Nephrology SRM Medical College Hospital and Research Centre  Kattankulathur Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1967-4470","authenticated-orcid":false,"given":"Gerry George","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Nephrology SRM Medical College Hospital and Research Centre  Kattankulathur Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7414-3210","authenticated-orcid":false,"given":"Suganya","family":"Muthukarupiah","sequence":"additional","affiliation":[{"name":"Department of Nephrology SRM Medical College Hospital and Research Centre  Kattankulathur Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9574-7403","authenticated-orcid":false,"given":"Sreedhar","family":"Sailapathy","sequence":"additional","affiliation":[{"name":"Department of Nephrology SRM Medical College Hospital and Research Centre  Kattankulathur Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5613-5252","authenticated-orcid":false,"given":"Ramachandran","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Dermatology SRM Medical College Hospital and Research Centre  Kattankulathur Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,3]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.12801"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000501035"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.165180"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2006.00982.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-4197-9.50035-1"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.02.007"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_831_21"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.148586"}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.14267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,17]],"date-time":"2024-03-17T23:41:23Z","timestamp":1710718883000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.14267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,3]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/nep.14267"],"URL":"https:\/\/doi.org\/10.1111\/nep.14267","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"type":"print","value":"1320-5358"},{"type":"electronic","value":"1440-1797"}],"subject":[],"published":{"date-parts":[[2024,1,3]]},"assertion":[{"value":"2023-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}