{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:23:58Z","timestamp":1783441438870,"version":"3.54.6"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T00:00:00Z","timestamp":1765670400000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The aetiology of crescentic glomerulonephritis is multifactorial, with anti\u2010neutrophil cytoplasmic antibody (ANCA)\u2010associated vasculitis (AAV) and anti\u2010glomerular basement membrane (GBM) antibody disease being well\u2010documented causes. Monoclonal immunoglobulin and immunoglobulin G4 (IgG4)\u2010related diseases can also exacerbate kidney damage through varying mechanisms. However, cases where both ANCA and anti\u2010GBM antibodies are positive, in the presence of serum M protein and elevated IgG4 levels, have not yet been reported. We herein report the first patient with dual ANCA and anti\u2010GBM antibody\u2010positive crescentic glomerulonephritis, along with monoclonal gammopathy and elevated IgG4 levels.<\/jats:p>","DOI":"10.1111\/nep.70157","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T05:44:10Z","timestamp":1765777450000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dual Anti\u2010Neutrophil Cytoplasmic Antibody and Anti\u2010Glomerular Basement Membrane Antibody\u2010Positive Crescentic Glomerulonephritis in a Patient With Monoclonal Gammopathy and Elevated\n                    <scp>IgG4<\/scp>\n                    Levels: A Case Report and Literature Review"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6744-0616","authenticated-orcid":false,"given":"Yu","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"},{"name":"NHC Key Laboratory of Clinical Nephrology (Sun Yat\u2010Sen University) and Guangdong Provincial Key Laboratory of Nephrology  Guangzhou China"},{"name":"Department of Nephrology Nanyang Central Hospital  Nanyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8613-7758","authenticated-orcid":false,"given":"Zhong","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"},{"name":"NHC Key Laboratory of Clinical Nephrology (Sun Yat\u2010Sen University) and Guangdong Provincial Key Laboratory of Nephrology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na\u2010Ya","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"},{"name":"NHC Key Laboratory of Clinical Nephrology (Sun Yat\u2010Sen University) and Guangdong Provincial Key Laboratory of Nephrology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian\u2010Wen","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"},{"name":"NHC Key Laboratory of Clinical Nephrology (Sun Yat\u2010Sen University) and Guangdong Provincial Key Laboratory of Nephrology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Fang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"},{"name":"NHC Key Laboratory of Clinical Nephrology (Sun Yat\u2010Sen University) and Guangdong Provincial Key Laboratory of Nephrology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0022-3784","authenticated-orcid":false,"given":"Feng\u2010Xian","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"},{"name":"NHC Key Laboratory of Clinical Nephrology (Sun Yat\u2010Sen University) and Guangdong Provincial Key Laboratory of Nephrology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"},{"name":"NHC Key Laboratory of Clinical Nephrology (Sun Yat\u2010Sen University) and Guangdong Provincial Key Laboratory of Nephrology  Guangzhou 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