{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:36:02Z","timestamp":1772998562935,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study aimed to determine the prevalence of mild cognitive impairment (MCI) and cognitive impairment (CI) in patients undergoing haemodialysis (HD) and to identify physical function characteristics associated with these conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted among 147 outpatients receiving HD. MCI was evaluated using the Japanese version of the Montreal Cognitive Assessment (MoCA\u2010J), and CI was assessed using the Mini\u2010Mental State Examination (MMSE). Patients were classified into three groups: normal (MMSE\u2009\u2265\u200924 and MoCA\u2010J\u2009\u2265\u200926), MCI (MMSE\u2009\u2265\u200924 and MoCA\u2010J\u2009&lt;\u200926) and CI (MMSE\u2009&lt;\u200924). Patient characteristics and physical function were compared among groups. Multivariate analysis was conducted using analysis of covariance adjusted for age, sex, dialysis vintage and body mass index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean age of participants was 69.7\u2009\u00b1\u200911.8\u2009years, 63.9% were male, and the mean HD vintage was 6.0\u2009\u00b1\u20096.9\u2009years. Based on cognitive testing, 50 patients (34%) were classified as normal, 59 (40%) as MCI and 38 (26%) as CI. Compared with the normal group, the CI group exhibited significantly lower physical function, including grip strength, Short Physical Performance Battery scores, and usual gait speed. Similarly, physical function in the CI group was significantly poorer than in the MCI group. However, no significant differences in physical function were observed in physical function between the normal and MCI groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>MCI and CI were prevalent among HD patients, affecting 40% and 26%, respectively. Patients with CI demonstrated a marked decline in physical function than those who were cognitively normal or had MCI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nep.70175","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T03:46:15Z","timestamp":1771386375000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Cognitive and Physical Functions in Patients Undergoing Haemodialysis"],"prefix":"10.1111","volume":"31","author":[{"given":"Yu","family":"Shimano","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Saiyu Clinic  Saitama Japan"},{"name":"Department of Physical Therapy Graduate School of Health Science, Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Saitoh","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Graduate School of Health Science, Juntendo University  Tokyo Japan"},{"name":"Department of Physical Therapy Faculty of Health Science, Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Matsuura","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Saiyu Clinic  Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Saiyu Clinic  Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/156720509788929237"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12199-020-00903-3"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.03066.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.897728"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-07550-4"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012050536"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.11.015"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2019.01.001"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2010.07.003"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-013-0367-2"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/nep.13173"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01947.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glx003"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xkme.2020.03.008"},{"key":"e_1_2_10_16_1","first-page":"834","article-title":"The Impact of Intradialytic Exercise on Activities of Daily Living and Physical Function in Hospitalized Hemodialysis Patients: A Study of Efficacy and Safety","volume":"8","author":"Takahashi R.","year":"2025","journal-title":"JMA Journal"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/16501970410017215"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1298\/ptr.R0033"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700046730"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0910237"},{"key":"e_1_2_10_21_1","unstructured":"World Health Organization \u201cRisk Reduction of Cognitive Decline and Dementia \u201d WHO Guidelines 2019."},{"key":"e_1_2_10_22_1","doi-asserted-by":"crossref","first-page":"e173","DOI":"10.1161\/CIR.0000000000001089","article-title":"American Heart Association Council on Cardiovascular and Stroke Nursing; Council on Hypertension; and Stroke Council. State of the Science: The Relevance of Symptoms in Cardiovascular Disease and Research: A Scientific Statement From the American Heart Association","volume":"146","author":"Jurgens C. Y.","year":"2022","journal-title":"Circulation"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2016.05.013"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-015-0174-1"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-020-1365-9"}],"container-title":["Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.70175","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nep.70175","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nep.70175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:52:47Z","timestamp":1772988767000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nep.70175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/nep.70175"],"URL":"https:\/\/doi.org\/10.1111\/nep.70175","archive":["Portico"],"relation":{},"ISSN":["1320-5358","1440-1797"],"issn-type":[{"value":"1320-5358","type":"print"},{"value":"1440-1797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70175"}}