{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:04:38Z","timestamp":1779681878512,"version":"3.53.1"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>\n                      Bartonella\n                      <jats:styled-content style=\"fixed-case\">henselae<\/jats:styled-content>\n                    <\/jats:italic>\n                    is an intracellular bacterium which classically causes cat scratch disease as well as culture\u2010negative endocarditis. We report a man in his 60s, with a mechanical aortic valve replacement who presented with a 6\u2010month fever of unknown origin (FUO), splenomegaly and acute kidney injury. Investigations showed discordant ANCA serologies, screening anti\u2010MPO positivity followed by confirmatory anti\u2010PR3 positivity, raising concern for ANCA\u2010associated vasculitis (AAV). However, renal biopsy demonstrated immune complex deposition, inconsistent with the pauci\u2010immune glomerulonephritis typical of AAV. Subsequent investigations revealed positive\n                    <jats:italic>Bartonella<\/jats:italic>\n                    serology and PCR. Transoesophageal echocardiography confirmed the diagnosis of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>B. henselae<\/jats:italic>\n                    <\/jats:styled-content>\n                    prosthetic valve endocarditis. He was treated with a prolonged course of rifampicin and doxycycline which led to clinical improvement. This case illustrates how\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>B. henselae<\/jats:italic>\n                    <\/jats:styled-content>\n                    can mimic AAV, with discordant ANCA results contributing to diagnostic uncertainty, and reinforces the need to consider alternative causes of ANCA positivity.\n                  <\/jats:p>","DOI":"10.1111\/nep.70224","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T03:55:47Z","timestamp":1779422147000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Discordant\n                    <scp>ANCA<\/scp>\n                    Positivity in Immune Complex Glomerulonephritis Secondary to\n                    <scp>\n                      <i>Bartonella henselae<\/i>\n                    <\/scp>\n                    Prosthetic Valve Endocarditis"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6358-3376","authenticated-orcid":false,"given":"Boris Long Hei","family":"Yow","sequence":"first","affiliation":[{"name":"Department of Medicine Middlemore Hospital  Otahuhu Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1040-5728","authenticated-orcid":false,"given":"Reina Carlin","family":"Kittaka","sequence":"additional","affiliation":[{"name":"Department of Medicine Middlemore Hospital  Otahuhu Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9865-5840","authenticated-orcid":false,"given":"Ching Shan Jason","family":"Yeung","sequence":"additional","affiliation":[{"name":"Department of Medicine Middlemore Hospital  Otahuhu Auckland New 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