{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T14:45:39Z","timestamp":1789397139838,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2025E110100"],"award-info":[{"award-number":["2025E110100"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["RS\u20102022\u2010KH130593"],"award-info":[{"award-number":["RS\u20102022\u2010KH130593"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Sleep duration is associated with cardiovascular events, mortality and rapidly declining kidney function in the general population. Less is known about its impact on transplant outcomes and health\u2010related quality of life (HRQOL) among kidney transplant recipients (KTRs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective multicenter longitudinal cohort study included 986 incident KTRs and investigated self\u2010reported sleep duration at the time of kidney transplantation. Analyses were performed to examine associations between sleep duration and biopsy\u2010proven acute rejection, death\u2010censored graft failure, major cardiovascular events, all\u2010cause mortality and HRQOL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During a median follow\u2010up period of 8\u2009years, the death\u2010censored graft failure rate was significantly higher among patients with sleep durations of \u2264\u20095\u2009h (adjusted hazard ratio [aHR], 3.69; 95% confidence interval [CI], 1.42\u20139.57;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007), 6\u2009h (aHR, 3.25; 95% CI, 1.34\u20137.87;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009), 8\u2009h (aHR, 2.93; 95% CI, 1.22\u20137.01;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016) and \u2265\u20099\u2009h (aHR, 3.58; 95% CI, 1.29\u20139.93;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014), compared to patients with a 7\u2010h sleep duration. Sleep duration was not significantly associated with biopsy\u2010proven acute rejection, major cardiovascular events or all\u2010cause mortality. Multivariable linear regression demonstrated that shorter sleep duration (\u2264\u20095\u2009h) was associated with lower HRQOL, indicated by decreases in the physical component summary score (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      , \u22124.51; 95% CI, \u22128.75 to \u22120.26;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.038) and mental component summary score (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      , \u22125.47; 95% CI, \u221210.29 to \u22120.65;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.026), relative to patients with a 7\u2010h sleep duration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Compared to a 7\u2010h sleep duration, both shorter and longer sleep durations were associated with a significantly higher risk of death\u2010censored graft failure among incident KTRs. Additionally, short sleep duration was significantly correlated with impaired HRQOL.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      NCT02042963;\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link>\n                      identifier\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nep.70229","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T02:56:02Z","timestamp":1780023362000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Self\u2010Reported Sleep Duration, Death\u2010Censored Graft Failure and Health\u2010Related Quality of Life Among Kidney Transplant Recipients: Results From the\n                    <scp>KNOW<\/scp>\n                    \u2010\n                    <scp>KT<\/scp>\n                    Study"],"prefix":"10.1111","volume":"31","author":[{"given":"Hee\u2010Yeon","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, School of Medicine Kyungpook National University, Kyungpook National University Hospital  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Jin","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Statistics Kyungpook National University  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu Ha","family":"Huh","sequence":"additional","affiliation":[{"name":"Department of Surgery Yonsei University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9117-2278","authenticated-orcid":false,"given":"Jae Berm","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Surgery, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung\u2010Gyu","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Korea University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Pyo","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chonbuk National University Hospital  Jeonju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungyeup","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Keimyung University School of Medicine  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7031-5214","authenticated-orcid":false,"given":"Jang\u2010Hee","family":"Cho","sequence":"additional","affiliation":[{"name":"Department 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