{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T01:33:23Z","timestamp":1793064803264,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare the observed rates of kidney transplantation among highly and non\u2010highly sensitised patients on the deceased donor waiting list in Aotearoa New Zealand, and characterise associations with high sensitisation, to inform potential changes in the National Kidney Allocation Scheme.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients listed for deceased donor kidney transplantation between 2006 and 2019 were identified using linked health data from the AcceSS and Equity in Transplantation platform. Highly sensitised patients were defined as having a panel reactive antibody (PRA) or calculated panel reactive antibody (cPRA) \u2265\u200980%, then stratified into groups of 80\u201394, 95\u201398 and \u2265\u200999%. Individual\u2010level characteristics associated with sensitisation were identified using linear regression, and transplantation rates between sensitisation groups were compared using a Cox proportional hazards model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Factors associated with increased sensitisation included prior transplant, female sex, younger age and non\u2010European ethnicity (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Increasing sensitisation was associated with reduced transplantation rate (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Compared with PRA\/cPRA &lt;\u200980%, the chance of transplantation was lower for those with PRA\/cPRA 80%\u201394% (HR: 0.75, 95% CI: 0.54\u20131.04), PRA\/cPRA 95%\u201398% (HR: 0.38, 95% CI: 0.23\u20130.60) and PRA\/cPRA \u2265\u200999% (HR: 0.10, 95% CI: 0.05\u20130.17).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Highly sensitised patients on the deceased donor waiting list in Aotearoa New Zealand experience reduced rates of kidney transplantation. The lowest rates are seen in patients with a cPRA of \u2265\u200999%, which highlights this group as a key target population for future modifications to the National Kidney Allocation Scheme.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nep.70295","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:01:47Z","timestamp":1792072907000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rates of Deceased Donor Kidney Transplantation in Highly Sensitised Patients in Aotearoa New Zealand: A Data Linkage Analysis"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7993-5819","authenticated-orcid":false,"given":"Amy O. R.","family":"Thomas","sequence":"first","affiliation":[{"name":"Department of Nephrology Te Whatu Ora Waitaha Canterbury  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6077-0862","authenticated-orcid":false,"given":"James A.","family":"Hedley","sequence":"additional","affiliation":[{"name":"Centre for Organ Donation Evidence University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9592-3167","authenticated-orcid":false,"given":"Reshma","family":"Shettigar","sequence":"additional","affiliation":[{"name":"Department of Nephrology Te Whatu Ora Waitaha Canterbury  Christchurch New Zealand"},{"name":"New Zealand Transplantation and Immunogenetics Laboratory, New Zealand Blood Service  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0432-1876","authenticated-orcid":false,"given":"Nicholas B.","family":"Cross","sequence":"additional","affiliation":[{"name":"Department of Nephrology Te Whatu Ora Waitaha Canterbury  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3814-6585","authenticated-orcid":false,"given":"Ian","family":"Dittmer","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine Auckland City Hospital, Te Whatu Ora Te Toka Tumai  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6615-4490","authenticated-orcid":false,"given":"Heather","family":"Dunckley","sequence":"additional","affiliation":[{"name":"New Zealand Transplantation and Immunogenetics Laboratory, New Zealand Blood Service  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7509-0512","authenticated-orcid":false,"given":"Angela C.","family":"Webster","sequence":"additional","affiliation":[{"name":"Centre for Organ Donation Evidence University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Transplant and Renal Medicine Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03686.x"},{"key":"e_1_2_9_3_1","unstructured":"Organ Donation New Zealand Annual Report 2023(Organ Donation New Zealand 2024) https:\/\/donor.co.nz\/assets\/Uploads\/2023\u2010Annual\u2010Report\/JD1666\u2010NZBS\u20102023\u2010ODNZ\u2010Annual\u2010Report.pdf."},{"key":"e_1_2_9_4_1","volume-title":"ANZDATA Annual Report 2024","author":"Sun 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