{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:15:19Z","timestamp":1787015719406,"version":"build-2736575974"},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Medtronic Preclinical Research Funding"}],"content-domain":{"domain":["neuromodulationjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuromodulation: Technology at the Neural Interface"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1111\/ner.12360","type":"journal-article","created":{"date-parts":[[2015,10,30]],"date-time":"2015-10-30T12:10:38Z","timestamp":1446207038000},"page":"101-107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Optimization of Neuromodulation for Bladder Control in a Rat Cystitis Model"],"prefix":"10.1016","volume":"19","author":[{"given":"Xin","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Nickles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dwight E.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/ner.12360_bib1","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1097\/00005392-199805000-00028","article-title":"Sacral nerve root neuromodulation: an effective treatment for refractory urge incontinence","volume":"159","author":"Shaker","year":"1998","journal-title":"J Urol"},{"key":"10.1111\/ner.12360_bib2","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1100\/tsw.2007.173","article-title":"Neuromodulation for lower urinary tract dysfunction\u2014an update","volume":"7","author":"Hussain","year":"2007","journal-title":"Sci World J"},{"key":"10.1111\/ner.12360_bib3","doi-asserted-by":"crossref","first-page":"F477","DOI":"10.1152\/ajprenal.00515.2011","article-title":"Neuromodulation in a rat model of bladder micturition reflex","volume":"302","author":"Su","year":"2012","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1111\/ner.12360_bib4","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1471-2490-13-34","article-title":"Quantification of effectiveness of bilateral and unilateral neuromodulation in the rat bladder rhythmic contraction model","volume":"13","author":"Su","year":"2013","journal-title":"BMC Urol"},{"key":"10.1111\/ner.12360_bib5","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/j.1464-410X.2011.10789.x","article-title":"Effects of stimulation site and stimulation parameters on bladder inhibition by electrical nerve stimulation","volume":"110","author":"Snellings","year":"2012","journal-title":"BJU Int"},{"key":"10.1111\/ner.12360_bib6","doi-asserted-by":"crossref","first-page":"F710","DOI":"10.1152\/ajprenal.00334.2012","article-title":"Neural pathways involved in sacral neuromodulation of reflex bladder activity in cats","volume":"304","author":"Zhang","year":"2013","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1111\/ner.12360_bib7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/nau.20612","article-title":"Animal models of sacral neuromodulation for detrusor overactivity","volume":"28","author":"Vignes","year":"2009","journal-title":"Neurourol Urodyn"},{"key":"10.1111\/ner.12360_bib8","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.urology.2009.04.025","article-title":"The effects of sacral acupuncture on acetic acid-induced bladder irritation in conscious rats","volume":"75","author":"Hino","year":"2010","journal-title":"Urology"},{"key":"10.1111\/ner.12360_bib9","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1152\/jn.1993.69.2.395","article-title":"Receptive properties of myelinated primary afferents innervating the inflamed urinary bladder of the cat","volume":"69","author":"H\u00e4bler","year":"1993","journal-title":"J Neurophysiol"},{"key":"10.1111\/ner.12360_bib10","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1152\/jn.1994.72.5.2420","article-title":"Mechanosensitive properties of pelvic nerve afferent fibers innervating the urinary bladder of the rat","volume":"72","author":"Sengupta","year":"1994","journal-title":"J Neurophysiol"},{"key":"10.1111\/ner.12360_bib11","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2490-13-70","article-title":"Neuromodulation attenuates bladder hyperactivity in a rat cystitis model","volume":"13","author":"Su","year":"2013","journal-title":"BMC Urol"},{"key":"10.1111\/ner.12360_bib12","doi-asserted-by":"crossref","first-page":"F53","DOI":"10.1152\/ajprenal.00090.2013","article-title":"The role of the endogenous opioid system in modulation of urinary bladder activity by spinal nerve stimulation","volume":"305","author":"Su","year":"2013","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1111\/ner.12360_bib13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/nau.22506","article-title":"Differentiation and interaction of tibial versus spinal nerve stimulation for micturition control in the rat","volume":"34","author":"Su","year":"2015","journal-title":"Neurourol Urodyn"},{"key":"10.1111\/ner.12360_bib14","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/ar.1091830408","article-title":"Distribution of lumbar and sacral afferent axons in submucosa of cat urinary bladder","volume":"183","author":"Uemura","year":"1975","journal-title":"Anat Rec"},{"key":"10.1111\/ner.12360_bib15","doi-asserted-by":"crossref","first-page":"R695","DOI":"10.1152\/ajpregu.1997.272.2.R695","article-title":"Pressure, volume, and chemosensitivity in afferent innervation of urinary bladder in rats","volume":"272","author":"Moss","year":"1997","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1111\/ner.12360_bib16","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1152\/jn.1997.77.3.1566","article-title":"Effects of opioids on mechanosensitive pelvic nerve afferent fibers innervating the urinary bladder of the rat","volume":"77","author":"Su","year":"1997","journal-title":"J Neurophysiol"},{"key":"10.1111\/ner.12360_bib17","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1002\/nau.21108","article-title":"Rodent models for urodynamic investigation","volume":"30","author":"Andersson","year":"2011","journal-title":"Neurourol Urodyn"},{"key":"10.1111\/ner.12360_bib18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/luts.12000","article-title":"Effect of sacral neuromodulation rate on overactive bladder symptoms: a randomized crossover feasibility study","volume":"5","author":"Peters","year":"2013","journal-title":"LUTS"},{"key":"10.1111\/ner.12360_bib19","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/nau.22556","article-title":"The effects of bilateral bipolar sacral neurostimulation on urinary bladder activity during filling before and after irritation in a rat model","volume":"34","author":"Dieter","year":"2015","journal-title":"Neurourol Urodyn"},{"key":"10.1111\/ner.12360_bib20","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0022-5347(17)52127-8","article-title":"The neurophysiological basis of bladder inhibition in response to intravaginal electrical stimulation","volume":"129","author":"Lindstrom","year":"1983","journal-title":"J Urol"}],"container-title":["Neuromodulation: Technology at the Neural Interface"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fner.12360","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094715921048789?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094715921048789?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ner.12360\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T21:52:52Z","timestamp":1761083572000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1094715921048789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S1094715921048789"],"URL":"https:\/\/doi.org\/10.1111\/ner.12360","relation":{},"ISSN":["1094-7159"],"issn-type":[{"value":"1094-7159","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optimization of Neuromodulation for Bladder Control in a Rat Cystitis Model","name":"articletitle","label":"Article Title"},{"value":"Neuromodulation: Technology at the Neural Interface","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ner.12360","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 International Neuromodulation Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}