{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T04:28:04Z","timestamp":1776918484162,"version":"3.51.2"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T00:00:00Z","timestamp":1478736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:p>We report a case of multiple calcifying pseudoneoplasms of the neuraxis (MCAPNON) with associated multifocal perivascular microcalcifications and vascular calcinosis. Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a very rare condition that may arise in extra\u2010axial and occasionally, in intra\u2010axial locations. Moreover, it is nearly always a solitary mass with only one case with two lesions reported. While the etiology and pathogenesis of CAPNON remains unclear, the histopathology findings of this entity have been well described. We report a case of a 62\u2010year\u2010old woman with 18 calcifying radiologic lesions involving bilateral cerebral hemispheres. Histologically, these lesions have features similar to that reported for CAPNON, including nodular calcification with fibro\u2010osseous components and peripheral histiocytic reaction. The patient had a poorly documented diagnosis of neurocyticercosis 32\u00a0years prior, although without tissue confirmation. The lack of detectable cysticercus serum antibody titers, and absence of residual larval or cyst wall tissue render multifocal calcific involution of that parasite unprovable although still plausible. We also raise the possibility of a blood\u2013brain barrier derangement and\/or a metabolic disorder as an alternative etiology. Whether this case of MCAPNON shares the same pathogenesis as the usual solitary CAPNON is unclear.<\/jats:p>","DOI":"10.1111\/neup.12349","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T15:10:11Z","timestamp":1478790611000},"page":"233-240","source":"Crossref","is-referenced-by-count":18,"title":["Multiple calcifying pseudoneoplasms of the neuraxis (MCAPNON): Distinct entity, CAPNON variant, or old neurocysticercosis?"],"prefix":"10.1111","volume":"37","author":[{"given":"Maram","family":"Abdaljaleel","sequence":"first","affiliation":[{"name":"Department of Pathology, Jordan University Hospital University of Jordan  Amman Jordan"},{"name":"Department of Pathology and Laboratory Medicine (Neuropathology) University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajarshi","family":"Mazumder","sequence":"additional","affiliation":[{"name":"Department of Neurology University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chirag B.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Neurology University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyuseok","family":"Im","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine (Neuropathology) University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Whitney","family":"Pope","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences (Neuroradiology) University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda M.","family":"Liau","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, David Geffen School of Medicine University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry V.","family":"Vinters","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine (Neuropathology) University of California at Los Angeles  Los Angeles CA USA"},{"name":"Department of Neurology University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William H.","family":"Yong","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine (Neuropathology) University of California at Los Angeles  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.72.1.0042"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1505"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199910000-00013"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1984.60.6.1308"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/neup.12198"},{"key":"e_1_2_6_7_1","first-page":"786","article-title":"Calculi within the brain. 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