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Imaging studies showed severe ventriculomegaly involving the lateral and third ventricles with multiple septated cysts noted in the lateral ventricles predominantly near the frontal horns. Histopathologic examination of the excised brain lesion revealed choroid plexus tissue and adjacent cerebral parenchyma with several non\u2010caseating granulomas. Granulomatous inflammation was also identified in mediastinal lymph nodes. By using specific monoclonal antibodies, <jats:italic>Propionibacterium acnes (P. acnes)<\/jats:italic> were detected in non\u2010caseating granulomas of both the brain and mediastinal lymph nodes. No acid\u2010fast bacilli or fungal elements were present. To the best of our knowledge, this is the first demonstration of <jats:italic>P. acnes<\/jats:italic> in sarcoid granulomas of cerebral tissue, and it reinforces the possible link between <jats:italic>P. acnes<\/jats:italic> and sarcoidosis.<\/jats:p>","DOI":"10.1111\/neup.12411","type":"journal-article","created":{"date-parts":[[2017,8,31]],"date-time":"2017-08-31T11:14:23Z","timestamp":1504178063000},"page":"159-164","source":"Crossref","is-referenced-by-count":15,"title":["<i>Propionibacterium acnes<\/i>\u2010associated neurosarcoidosis: A case report with review of the literature"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8379-7478","authenticated-orcid":false,"given":"Guang","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Loma Linda University Medical Center  Loma Linda California 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