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Autopsy findings showed degeneration of the hypoglossal nuclei, prominent neuronal loss and atrophy in the anterior horn of the whole spinal cord despite the presence of mild astrocytosis, degeneration of the gracilis on one side, and infiltration of inflammatory cells, which included B cells and plasma cells in the anterior and posterior roots of the lumbar spinal cord, iliopsoas muscle, and perivascular area of the cervical cord. On immunostaining, cytoplasmic inclusions of phosphorylated transactivation response DNA\u2010binding protein of 43\u2009kDa were observed in the motor neurons and astrocytes of the hypoglossal nuclei and whole spinal cord. The final diagnosis was paraneoplastic lower motor neuron disease with sensorimotor neuropathy due to Waldenstr\u00f6m's macroglobulinemia.<\/jats:p>","DOI":"10.1111\/neup.12506","type":"journal-article","created":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T02:39:56Z","timestamp":1534732796000},"page":"568-573","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Autopsy\u2010proven case of paraneoplastic lower motor neuron disease with sensorimotor neuropathy due to Waldenstr\u00f6m's macroglobulinemia"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1245-8890","authenticated-orcid":false,"given":"Yasuhiro","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Neurology Asahikawa Medical Center  Asahikawa Japan"},{"name":"Department of Clinical Research Asahikawa Medical Center  Asahikawa 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