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Histopathological investigations confirmed a grade 2 ependymoma according to the World Health Organization classification. Genetic analysis revealed a tumor harboring <jats:italic>FAM118B<\/jats:italic> fusion to <jats:italic>YAP1<\/jats:italic>, and no other genetic alterations or methylation of the O<jats:sup>6<\/jats:sup>\u2010methylguanine\u2010DNA methyltransferase gene promoter  were detected. 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