{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:17:26Z","timestamp":1787015846884,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>Chronic graft\u2010versus\u2010host disease (cGVHD) is the most important complication resulting in the death of bone marrow transplantation (BMT) survivors. It is also a relatively rare cause of inflammatory myopathy (IM). We report the case of a 46\u2010year\u2010old woman who developed severe cGVHD\u2010related IM after BMT for myelodysplastic syndrome. She presented with severe muscle pain and weakness with cGVHD\u2010related symptoms in other organs. Myopathological analysis showed moderate cell infiltration with remarkable necrotic and regenerative fibers. Sarcoplasm and capillaries expressed C5b9 and myxovirus resistance protein 1. Non\u2010necrotic fibers in perifascicular regions expressed MHC\u2010II. Steroid therapy did not sufficiently control cGVHD\u2010related IM, and the patient was concurrently treated with an immunosuppressant. Our findings show that IM is a key manifestation of cGVHD and that the expression of interferon\u2010inducible proteins in muscle pathology is useful for identifying cGVHD\u2010related IM.<\/jats:p>","DOI":"10.1111\/neup.12816","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T19:49:35Z","timestamp":1651693775000},"page":"309-314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Pathological features of inflammatory myopathy as a manifestation of chronic graft\u2010versus\u2010host disease after allogeneic bone marrow transplantation"],"prefix":"10.1111","volume":"42","author":[{"given":"Tomo","family":"Shiota","sequence":"first","affiliation":[{"name":"Department of Neurology Nara Medical University School of Medicine  Kashihara 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