{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:13:31Z","timestamp":1780514011475,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:00:00Z","timestamp":1685404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Tuberculosis of the hypothalamo\u2013pituitary axis is extremely uncommon. The presentation of panhypopituitarism in a case of sellar tuberculosis is an even rarer occurrence. We present a case of a 44\u2010year\u2010old man who presented with complaints of headache and right\u2010sided diminution of vision for six\u2009months. A hormone profile showed abnormal anterior pituitary assay suggestive of panhypopituitarism. Magnetic Resonance imaging of the brain showed a sellar mass measuring 1.8\u2009\u00d7\u20091.5\u2009\u00d7\u20091.3\u2009cm with suprasellar extension suggestive of a pituitary adenoma. Histopathological examination showed multiple epithelioid cell granulomas along with Langhans giant cells and mixed inflammatory infiltrates against a necrotic background. Zeihl Neelson stain demonstrated the presence of acid\u2010fast bacilli. Thus, a final diagnosis of pituitary tuberculoma was made, and the patient started on antitubercular therapy. It is extremely important to correctly diagnose sellar tuberculosis as the treatment is entirely different, and the patient usually responds well to therapy.<\/jats:p>","DOI":"10.1111\/neup.12925","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T05:28:33Z","timestamp":1685510913000},"page":"496-499","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pituitary tuberculoma with panhypopituitarism masquerading as a pituitary adenoma"],"prefix":"10.1111","volume":"43","author":[{"given":"Adil","family":"Aziz Khan","sequence":"first","affiliation":[{"name":"Department of Pathology Vardhman Mahavir Medical College and Safdarjung Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4630-016X","authenticated-orcid":false,"given":"Sana","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Pathology Vardhman Mahavir Medical College and Safdarjung Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaivy","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Pathology Vardhman Mahavir Medical College and Safdarjung Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saba","family":"Naaz","sequence":"additional","affiliation":[{"name":"Department of Pathology Vardhman Mahavir Medical College and Safdarjung Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8044-4327","authenticated-orcid":false,"given":"Sufian","family":"Zaheer","sequence":"additional","affiliation":[{"name":"Department of Pathology Vardhman Mahavir Medical College and Safdarjung Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2008.12.032"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00042-07"},{"key":"e_1_2_7_4_1","first-page":"77","article-title":"Pituitary tuberculoma: An uncommon pathology","volume":"1","author":"Gupta PK","year":"2021","journal-title":"Indian J Neurosurg"},{"key":"e_1_2_7_5_1","first-page":"50","article-title":"Sellar tuberculoma: A rare presentation in a 30\u2010year\u2010old Ethiopian woman: Case report","volume":"38","author":"Ayele BA","year":"2019","journal-title":"Afr J Neurol Sci"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/2277-5706.241241"},{"key":"e_1_2_7_7_1","first-page":"1076","article-title":"Diffuse tuberculosis of the pituitary gland simulating tumor, with postoperative recovery","volume":"44","author":"Coleman CC","year":"1940","journal-title":"J Nerv Ment Dis"},{"key":"e_1_2_7_8_1","first-page":"453","article-title":"Pituitary tuberculosis","volume":"55","author":"Sunil K","year":"2007","journal-title":"J Assoc Physicians India"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ando.2015.02.001"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-017-1654-4"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2016.07.012"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(00)00063-9"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0967-5868(03)00140-1"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/ajns.AJNS_371_20"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-006-5420-2"}],"container-title":["Neuropathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/neup.12925","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T05:32:29Z","timestamp":1702963949000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/neup.12925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,30]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1111\/neup.12925"],"URL":"https:\/\/doi.org\/10.1111\/neup.12925","archive":["Portico"],"relation":{},"ISSN":["0919-6544","1440-1789"],"issn-type":[{"value":"0919-6544","type":"print"},{"value":"1440-1789","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,30]]},"assertion":[{"value":"2023-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}