{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:15:29Z","timestamp":1788437729375,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001111","name":"Cancer Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016057","name":"Robert Connor Dawes Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>Ependymal tumors are classified based on their location, histology, and molecular characteristics. Supratentorial ependymomas (ST\u2010EPNs) are a group of circumscribed supratentorial gliomas, which usually have pathogenic fusions involving either zinc finger translocation associated <jats:italic>(ZFTA) (formerly C11orf95) or YAP1<\/jats:italic>. A subtype of ependymoma was recently described and labeled ependymoma\u2010like tumors with mesenchymal differentiation (ELTMDs). We describe a case of a 5\u2010year\u2010old boy who presented with a right frontal tumor. The diagnosis was challenging, and a correct diagnosis could only be reached after reanalysis of methylation data with a more recent version of the classifier and RNA fusion testing, which revealed <jats:italic>ZFTA:NCOA1<\/jats:italic> (nuclear receptor coactivator 1) fusion. There are only a handful of cases of this entity, which is being reported for its rarity and the diagnostic challenge it poses.<\/jats:p>","DOI":"10.1111\/neup.12952","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:54:20Z","timestamp":1699318460000},"page":"216-221","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Ependymoma\u2010like tumor with mesenchymal differentiation (<scp>ELTMD<\/scp>) with <i>ZFTA:NCOA1<\/i> fusion: A diagnostic challenge"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7755-8745","authenticated-orcid":false,"given":"Pranav","family":"Dorwal","sequence":"first","affiliation":[{"name":"Diagnostic Genomics, Monash Health  Clayton Australia"},{"name":"Anatomical Pathology, Monash Health  Clayton Australia"},{"name":"School of Clinical Sciences Monash University  Clayton Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5920-0029","authenticated-orcid":false,"given":"Christine","family":"White","sequence":"additional","affiliation":[{"name":"Victorian Clinical Genetics Services  Parkville Australia"},{"name":"Centre for Cancer Research Hudson Institute of Medical Research  Clayton Australia"},{"name":"Molecular and Translational Science Monash University  Clayton Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna FN","family":"Goh","sequence":"additional","affiliation":[{"name":"Diagnostic Genomics, Monash Health  Clayton Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Kumar","sequence":"additional","affiliation":[{"name":"Diagnostic Genomics, Monash Health  Clayton Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"McEniery","sequence":"additional","affiliation":[{"name":"Radiology Queensland Children's Hospital  South Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick","family":"Walker","sequence":"additional","affiliation":[{"name":"Oncology Queensland Children's Hospital  South Brisbane Australia"},{"name":"Oncology Princess Alexandra Hospital  Woolloongabba Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Robertson","sequence":"additional","affiliation":[{"name":"Neuropathology Royal Brisbane &amp; Women's Hospital  Herston Australia"},{"name":"Medical School The University of Queensland  Herston Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,6]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Central nervous system tumours [Internet]","author":"WHO Classification of Tumours Editorial Board","year":"2021"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12943"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14879"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12866"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13109"},{"key":"e_1_2_9_7_1","first-page":"13","article-title":"Supratentorial ependymoma, zinc finger translocation\u2010associated fusion positive, with extensive synaptophysin immunoreactivity arising from malignant transformation of clear cell ependymoma: A case report. 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