{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T19:59:59Z","timestamp":1770062399149,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T00:00:00Z","timestamp":1737849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:p>We report a rare case of rhabdoid meningioma (RM) originating from the optic nerve in a 57\u2010year\u2010old female. The tumor exhibited rhabdoid or epithelioid histology and harbored BAP1 inactivation mutations. Optic nerve meningioma typically originates from the outer meningeal cells of the optic nerve within the optic canal and is usually benign, with most cases classified as meningothelial or transitional meningiomas. This is the first reported case of RM involving the optic nerve, presenting with World Health Organization (WHO) central nervous system (CNS) grade 1 histological features but without CDKN2A\/B homozygous deletions or telomerase reverse transcriptase promoter mutations, though harboring a BAP1 deletion. Despite being classified as a low\u2010grade tumor by current standards, the rapid recurrence and progression observed underscore the importance of reporting this case to enhance awareness among pathologists and reduce misdiagnoses.<\/jats:p>","DOI":"10.1111\/neup.13028","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T02:20:17Z","timestamp":1737944417000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A case of rhabdoid meningioma originating from the optic nerve"],"prefix":"10.1111","volume":"45","author":[{"given":"Jing","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Pathology Shenzhen Second People's Hospital, Shenzhen University 1st Affiliated Hospital  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziling","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Pathology Shenzhen Second People's Hospital, Shenzhen University 1st Affiliated Hospital  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Radiology Shenzhen Second People's Hospital, Shenzhen University 1st Affiliated Hospital  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2392-0454","authenticated-orcid":false,"given":"Xia","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pathology Shenzhen Second People's Hospital, Shenzhen University 1st Affiliated Hospital  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,26]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"231","volume-title":"WHO Classification of Tumours of the Central Nervous System","author":"Louis DN","year":"2016"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199812000-00005"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199802000-00012"},{"key":"e_1_2_10_5_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0306386","article-title":"Characterization of somatic mutations in sporadic uveal melanoma and uveal melanoma in patients with germline BAP1 pathogenic variants","volume":"19","author":"Karin AW","year":"2024","journal-title":"PLoS One"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-024-03196-4"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13133960"},{"key":"e_1_2_10_8_1","first-page":"130","article-title":"Combination of EZH2 and ATM inhibition in BAP1\u2010deficient mesothelioma","volume":"130","author":"Nick L","year":"2024","journal-title":"Br J Cancer"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00787-5"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.909"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-19-1220"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000615"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/nox094"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/nox094"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2017.11.010"}],"container-title":["Neuropathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/neup.13028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T12:37:54Z","timestamp":1754397474000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/neup.13028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,26]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1111\/neup.13028"],"URL":"https:\/\/doi.org\/10.1111\/neup.13028","archive":["Portico"],"relation":{},"ISSN":["0919-6544","1440-1789"],"issn-type":[{"value":"0919-6544","type":"print"},{"value":"1440-1789","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,26]]},"assertion":[{"value":"2024-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13028"}}