{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T06:48:43Z","timestamp":1782197323371,"version":"3.54.5"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropathology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A surgical case of lymphoplasmacyte\u2010rich (LPR) meningioma that arose in the region of the clivus of an 81\u2010year\u2010old woman is reported. The tumor consisted largely of a dense and diffuse infiltration of mature lymphocytes and a smaller number of plasma cells. Mainly in the peripheral region of the tumor, small sheets or clusters of large polygonal cells having vesicular nuclei and palely eosinophilic cytoplasm were observed. Some of these cells formed cellular whorls. These cells showed immunoreactivity for progesterone receptor, epithelial membrane antigen, somatostatin receptor type 2A, epithelial cadherin, and podoplanin, thus confirming the diagnosis of LPR meningioma. Although lymph follicles having germinal centers were not evident, the distributions of lymphocytes and plasma cells were heterogeneous, and plasma cells occasionally appeared to surround lymphocytic aggregates. Some intratumoral venules showed features of \u201chigh endothelial venules.\u201d These findings suggested that a dense accumulation of lymphocytes and plasma cells in LPR meningioma was not a simple inflammatory cell infiltration but might represent formation of \u201ctertiary lymphoid structures.\u201d Whereas some inflammatory cells showed cytoplasmic immunoreactivity for programmed cell death ligand\u20101, meningioma cells did not express it.<\/jats:p>","DOI":"10.1111\/neup.70059","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:54:41Z","timestamp":1777942481000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lymphoplasmacyte\u2010Rich Meningioma: Possible Formation of Intratumoral \u201cTertiary Lymphoid Structures\u201d"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7162-9293","authenticated-orcid":false,"given":"Masayuki","family":"Shintaku","sequence":"first","affiliation":[{"name":"Department of Pathology Kansai Medical University Hospital  Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Hamamoto","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Kansai Medical University Hospital  Hirakata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Hashiba","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Kansai Medical University Hospital  Hirakata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Nonaka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Kansai Medical University Hospital  Hirakata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeo","family":"Nakaya","sequence":"additional","affiliation":[{"name":"Department of Pathology Kansai Medical University Hospital  Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsunori","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Pathology Kansai Medical University Hospital  Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Tsuta","sequence":"additional","affiliation":[{"name":"Department of Pathology Kansai Medical University Hospital  Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197901)43:1<258::AID-CNCR2820430137>3.0.CO;2-9"},{"key":"e_1_2_11_3_1","first-page":"504","article-title":"Lymphoplasmacyte\u2010Rich Meningioma. 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