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Higher GEI scores were linked to elevated dementia incidence among women and an expanding female\u2013male disparity, with the strongest associations observed in resource\u2010limited countries undergoing rapid social and lifestyle transitions. Multiple regression identified GEI as the most significant predictor of both female dementia incidence and gender disparity, while economic affluence and urbanization showed no independent effects. Findings highlight a paradox: although gender equality advances women's access to education, employment, and healthcare, it may simultaneously increase exposure to dementia\u2010related risk factors, including chronic stress, work\u2013life imbalance, and lifestyle changes such as greater smoking and alcohol use. These results emphasize the importance of gender\u2010sensitive public health strategies that address unintended health consequences of social progress. Interventions should prioritize stress management, workplace mental health, and lifestyle modification while accounting for disproportionate caregiving responsibilities, thereby supporting equitable cognitive health outcomes for women worldwide.<\/jats:p>","DOI":"10.1111\/nhs.70230","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T05:40:59Z","timestamp":1758087659000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Dementia Risk and Gender Equality: Global Insights Into Social Determinants"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6229-1064","authenticated-orcid":false,"given":"Wenpeng","family":"You","sequence":"first","affiliation":[{"name":"School of Biomedicine The University of Adelaide  Adelaide Australia"},{"name":"School of Nursing and Midwifery Western Sydney University  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,16]]},"reference":[{"issue":"8","key":"e_1_2_13_2_1","article-title":"The Role of Estrogen Therapy as a Protective Factor for Alzheimer's Disease and Dementia in Postmenopausal Women: A Comprehensive Review of the Literature","volume":"15","author":"Ali N.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000201369"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/14713012231220963"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/14747049231210245"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.14410"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-024-01490-w"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci12020160"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000525677"},{"key":"e_1_2_13_10_1","volume-title":"United Nations Entity for Gender Equality and the Empowerment of Women (Discussion Paper No 41)","author":"Berik G.","year":"2022"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/tobaccocontrol-2014-051892"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000001706"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170098"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/socsci13020092"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaging.2024.101285"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102630"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0298750"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58081025"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-024-03642-2"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-210094"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-022-03086-4"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-27368-4"},{"key":"e_1_2_13_23_1","doi-asserted-by":"crossref","unstructured":"Gilles V. 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