{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:01:26Z","timestamp":1790136086256,"version":"4.0.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing &amp; Health Sciences"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study developed an evidence\u2010based nursing protocol for semi\u2010implantable IDDS and evaluated its effectiveness in managing refractory cancer pain to standardize practice. Using the Joanna Briggs Institute (JBI) evidence translation model, 34 best\u2010evidence statements were synthesized from literature (2015\u20132025) to construct a perioperative nursing protocol. This protocol was implemented in 32 patients (post\u2010implementation group) and compared to 31 pre\u2010implementation patients. Clinical outcomes, including analgesic effectiveness and adverse events, were evaluated, demonstrating the protocol's impact on improving patient care. The evidence\u2010based protocol significantly improved pain relief rates and patient satisfaction (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Overall adverse events, including infections, were reduced (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Compliance with all 12 nursing quality indicators improved, especially home care education (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Nursing staff also demonstrated significant gains in IDDS knowledge, attitudes, practices, and dressing\u2010change performance (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). An evidence\u2010based nursing protocol for semi\u2010implantable IDDS in refractory cancer pain improved pain control, implementation of this evidence\u2010based nursing protocol was associated with better pain control, fewer device\u2010related adverse events and higher patient satisfaction, which supports its feasibility for wider clinical practice.\n                  <\/jats:p>","DOI":"10.1111\/nhs.70408","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T23:35:47Z","timestamp":1786577747000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evidence\u2010Based Nursing Management of Semi\u2010Implantable Intrathecal Drug Delivery Systems for Refractory Cancer Pain: Protocol Development and Clinical Evaluation"],"prefix":"10.1111","volume":"28","author":[{"given":"Xu\u2010Ling","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Pain The Second Affiliated Hospital of Soochow University  Suzhou Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010Mei","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Nursing The Second Affiliated Hospital of Soochow University  Suzhou Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010Xia","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pain The Second Affiliated Hospital of Soochow University  Suzhou Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Pain The Second Affiliated Hospital of Soochow University  Suzhou Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pain The Second Affiliated Hospital of Soochow University  Suzhou Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3716-0181","authenticated-orcid":false,"given":"Li","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Operating Room The Second Affiliated Hospital of Soochow University  Suzhou Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010015\u20102678\u20109"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2025.01.003"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.5414\/CP204363"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1672\u20101756.2017.12.001"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2011.0326"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ner.12538"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurom.2022.03.003"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u2010030\u201081526\u20104_14"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000261"},{"key":"e_1_2_15_11_1","first-page":"90","volume-title":"Evidence\u2010Based Nursing Second Edition","author":"Hu Y.","year":"2018"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.12019\/j.issn.1671?5144.2021.02.006"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000547446"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1006\u20109852.2023.03.012"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40122\u2010023\u201000507\u2010z"},{"issue":"2","key":"e_1_2_15_16_1","first-page":"1","article-title":"Intrathecal Drug Delivery Systems for Cancer Pain: A Health Technology Assessment","volume":"24","author":"Ontario Health","year":"2024","journal-title":"Ontario Health Technology Assessment Series"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916\u2010015\u20100488\u2010x"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265\u2010015\u20100471\u20101"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2024.10.019"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2021.101467"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2025.0032"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010015\u20103047\u20104"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pnaa364"},{"issue":"11","key":"e_1_2_15_24_1","first-page":"964","article-title":"JBI Evidence Pre\u2010Classification and Evidence Recommendation Level System (2014 Edition)","volume":"30","author":"Wang C. 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