{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:27:08Z","timestamp":1762507628725,"version":"3.40.5"},"reference-count":45,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,12,9]],"date-time":"2018-12-09T00:00:00Z","timestamp":1544313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare and evaluate the efficacy and safety of continuous and intermittent control of cuff pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a comprehensive and systematic meta\u2010analysis of randomized controlled trials (RCTs) assessing the continuous and intermittent control of P<jats:sub>cuff<\/jats:sub> by searching PUBMED, EMBASE and other such databases (from inception to 31 March 2018). Summary odds ratios or mean differences with 95% confidence intervals were calculated using a fixed\u2010 or random\u2010effects model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>Seven randomised controlled trials with 970 mechanically ventilated patients were included in this study. The continuous control of cuff pressure significantly reduced the incidence of cuff pressure &lt; 20 cm H<jats:sub>2<\/jats:sub>O (0.03 (OR) (95% CI: 0.01\u20130.07)), P<jats:sub>cuff<\/jats:sub> &gt; 30 cm H<jats:sub>2<\/jats:sub>O (0.06 (95% CI: 0.03\u20130.15)) and VAP (0.39 (95% CI: 0.28\u20130.55)) when compared with intermittent control of cuff pressure. No significant differences in duration of MV (\u20101.94 (95% CI: \u20104.06 to \u20100.17)), length of ICU stay (\u20103.88 (95% CI: \u20109.00 to \u20101.23)) and mortality (0.99 (95% CI: 0.73\u20131.35)) were found between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Continuous control of cuff pressure offers more benefits in stabilizing the cuff pressure and reducing the incidence of VAP, and more studies are warranted to further evaluate the role of continuous control of cuff pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to practice<\/jats:title><jats:p>The continuous control of cuff pressure should be conducted whenever possible as it is the most ideal for the prognosis of MV patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nicc.12393","type":"journal-article","created":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T07:29:34Z","timestamp":1544426974000},"page":"76-82","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Is continuous better than intermittent control of tracheal cuff pressure? 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