{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:46:19Z","timestamp":1747187179091,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T00:00:00Z","timestamp":1683244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>INTELLiVENT\u2010adaptive support ventilation (ASV) is an automated closed\u2010loop mode of invasive ventilation for use in critically ill patients. INTELLiVENT\u2010ASV automatically adjusts, without the intervention of the caregiver, ventilator settings to achieve the lowest work and force of breathing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this case series is to describe the specific adjustments of INTELLiVENT\u2010ASV in patients with acute hypoxemic respiratory failure, who were intubated for invasive ventilation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>We describe three patients with severe acute respiratory distress syndrome (ARDS) because of COVID\u201019 who received invasive ventilation in our intensive care unit (ICU) in the first year of the COVID\u201019 pandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>INTELLiVENT\u2010ASV could be used successfully, but only after certain adjustments in the settings of the ventilator. Specifically, the high oxygen targets that are automatically chosen by INTELLiVENT\u2010ASV when the lung condition \u2018ARDS\u2019 is ticked had to be lowered, and the titration ranges for positive end expiratory pressure (PEEP) and inspired oxygen fraction (FiO<jats:sub>2<\/jats:sub>) had to be narrowed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The challenges taught us how to adjust the ventilator settings so that INTELLiVENT\u2010ASV could be used in successive COVID\u201019 ARDS patients, and we experienced the benefits of this closed\u2010loop ventilation in clinical practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to clinical practice<\/jats:title><jats:p>INTELLiVENT\u2010ASV is attractive to use in clinical practice. It is safe and effective in providing lung\u2010protective ventilation. A closely observing user always remains needed. INTELLiVENT\u2010ASV has a strong potential to reduce the workload associated with ventilation because of the automated adjustments.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nicc.12924","type":"journal-article","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T09:00:27Z","timestamp":1683277227000},"page":"219-225","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Closed\u2010loop ventilation in <scp>COVID\u2010<\/scp>19 patients with acute hypoxemic respiratory failure\u2014A case series"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9569-2462","authenticated-orcid":false,"given":"Laura A.","family":"Buiteman\u2010Kruizinga","sequence":"first","affiliation":[{"name":"Department of Intensive Care Reinier de Graaf Hospital  Delft the Netherlands"},{"name":"Department of Intensive Care Amsterdam University Medical Centers, location 'AMC\u2019  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pim L. J.","family":"van der Heiden","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Reinier de Graaf Hospital  Delft the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederique","family":"Paulus","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Amsterdam University Medical Centers, location 'AMC\u2019  Amsterdam the Netherlands"},{"name":"ACHIEVE, Centre of Applied Research, Faculty of Health Amsterdam University of Applied Sciences  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus J.","family":"Schultz","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Amsterdam University Medical Centers, location 'AMC\u2019  Amsterdam the Netherlands"},{"name":"Mahidol\u2013Oxford Tropical Medicine Research Unit (MORU) Mahidol University  Bangkok Thailand"},{"name":"Nuffield Department of Medicine University of Oxford  Oxford United\u00a0Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,5]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_11_2_1","DOI":"10.1152\/jappl.1950.2.11.592"},{"doi-asserted-by":"publisher","key":"e_1_2_11_3_1","DOI":"10.1111\/j.1749-6632.1963.tb13500.x"},{"doi-asserted-by":"publisher","key":"e_1_2_11_4_1","DOI":"10.1016\/j.bja.2020.06.037"},{"doi-asserted-by":"publisher","key":"e_1_2_11_5_1","DOI":"10.1016\/j.hrtlng.2019.11.001"},{"doi-asserted-by":"publisher","key":"e_1_2_11_6_1","DOI":"10.1007\/s00134-022-06719-9"},{"doi-asserted-by":"publisher","key":"e_1_2_11_7_1","DOI":"10.1007\/s00134-018-5375-6"},{"doi-asserted-by":"publisher","key":"e_1_2_11_8_1","DOI":"10.1056\/NEJMsa1410639"},{"doi-asserted-by":"publisher","key":"e_1_2_11_9_1","DOI":"10.1016\/S2213-2600(20)30325-8"},{"doi-asserted-by":"publisher","key":"e_1_2_11_10_1","DOI":"10.1164\/rccm.201908-1545CI"},{"doi-asserted-by":"publisher","key":"e_1_2_11_11_1","DOI":"10.1007\/s00101-013-2158-x"},{"doi-asserted-by":"publisher","key":"e_1_2_11_12_1","DOI":"10.1056\/NEJM200005043421801"},{"doi-asserted-by":"publisher","key":"e_1_2_11_13_1","DOI":"10.1016\/j.jcrc.2022.154047"},{"issue":"23","key":"e_1_2_11_14_1","first-page":"2526","article-title":"Acute respiratory distress syndrome: the Berlin definition","volume":"307","author":"Ranieri VM","year":"2012","journal-title":"JAMA"},{"doi-asserted-by":"publisher","key":"e_1_2_11_15_1","DOI":"10.1056\/NEJMoa032193"},{"doi-asserted-by":"publisher","key":"e_1_2_11_16_1","DOI":"10.3390\/jcm10225409"},{"doi-asserted-by":"publisher","key":"e_1_2_11_17_1","DOI":"10.1177\/08850666211024139"},{"doi-asserted-by":"publisher","key":"e_1_2_11_18_1","DOI":"10.1080\/17476348.2021.1933450"},{"doi-asserted-by":"publisher","key":"e_1_2_11_19_1","DOI":"10.23736\/S0375-9393.17.11963-2"},{"issue":"6","key":"e_1_2_11_20_1","first-page":"657","article-title":"Closed\u2010loop ventilation mode (IntelliVent\u00ae\u2010ASV) in intensive care unit: a randomized trial","volume":"82","author":"Bialais E","year":"2016","journal-title":"Minerva Anestesiol"},{"doi-asserted-by":"publisher","key":"e_1_2_11_21_1","DOI":"10.1007\/s00134-012-2799-2"}],"container-title":["Nursing in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nicc.12924","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T10:16:05Z","timestamp":1706609765000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nicc.12924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,5]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/nicc.12924"],"URL":"https:\/\/doi.org\/10.1111\/nicc.12924","archive":["Portico"],"relation":{},"ISSN":["1362-1017","1478-5153"],"issn-type":[{"type":"print","value":"1362-1017"},{"type":"electronic","value":"1478-5153"}],"subject":[],"published":{"date-parts":[[2023,5,5]]},"assertion":[{"value":"2023-02-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}