{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T02:16:57Z","timestamp":1767925017398,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:00:00Z","timestamp":1706572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to evaluate the effect of cold application on amiodarone\u2010related vein phlebitis. A quasi\u2010experimental design was used. The study sample consisted of 79 patients who received an amiodarone infusion. The control group of the study consisted of patients receiving amiodarone treatment, while the intervention group consisted of patients receiving cold application during the amiodarone infusion. In the intervention group, after the start of amiodarone treatment, cold gel packs were applied a total of 12 times for 15\u2009min at 2\u2010h intervals. The rate of phlebitis development was 59% in the intervention group and 95% in the control group (<jats:italic>p<\/jats:italic> &lt; .001). It was found that 52.2% of the patients in the intervention group had first grade phlebitis and 84.4% of the patients in the control group who developed phlebitis had second grade phlebitis (<jats:italic>p<\/jats:italic> &lt; .001). The 15\u2010min cold application was found to be effective in terms of the rate of phlebitis development, phlebitis grade and time of phlebitis development. (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link> NCT05058053).<\/jats:p>","DOI":"10.1111\/nicc.13020","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T01:40:03Z","timestamp":1706665203000},"page":"1739-1743","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The effect of cold gel pack application in the prevention of <scp>amiodarone\u2010related<\/scp> phlebitis"],"prefix":"10.1111","volume":"29","author":[{"given":"Burcu","family":"Okyay","sequence":"first","affiliation":[{"name":"Ankara City Hospital Cardiovascular Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5148-5034","authenticated-orcid":false,"given":"Tulay","family":"Basak","sequence":"additional","affiliation":[{"name":"Gulhane Faculty of Nursing University of Health Sciences Turkey  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4037\/ccn2012139"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2013460"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/1982-0194201600037"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000396"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1129729819838123"},{"issue":"3","key":"e_1_2_10_7_1","first-page":"370","article-title":"The effects of sesame oil on the prevention of amiodaron\u2010induced phlebitis","volume":"20","author":"Bagheri\u2010Nesami M","year":"2015","journal-title":"Iran J Nurs Midwifery Res"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvn.2016.11.001"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000081"},{"issue":"3","key":"e_1_2_10_10_1","first-page":"410","article-title":"A study to assess and compare the effectiveness of moist heat versus ice packs application in reducing the signs and symptoms of \u0131ntravenous cannulation induced thrombophlebitis among patients admitted in civil hospital of dausa district, Rajasthan","volume":"3","author":"Gauttam V","year":"2016","journal-title":"Ira\u2010Int J Appl Sci"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/24694193.2017.1386978"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/10376178.2016.1190289"},{"key":"e_1_2_10_13_1","unstructured":"Pun\u0131thavath\u0131R.The Effect of Glycerin Magnesium Sulphate Application Versus Cold Application on Thrombophlebitis among Patients Received Intravenous Therapy.2015."},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129804-200611000-00004"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.12669\/pjms.304.5067"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.26650\/FNJN296258"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/2377960820901370"}],"container-title":["Nursing in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nicc.13020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T10:36:01Z","timestamp":1732876561000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nicc.13020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,30]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/nicc.13020"],"URL":"https:\/\/doi.org\/10.1111\/nicc.13020","archive":["Portico"],"relation":{},"ISSN":["1362-1017","1478-5153"],"issn-type":[{"value":"1362-1017","type":"print"},{"value":"1478-5153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,30]]},"assertion":[{"value":"2023-04-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}