{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T06:18:29Z","timestamp":1787897909786,"version":"build-2784847793"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF\u20102020R1A6A1A03041989"],"award-info":[{"award-number":["NRF\u20102020R1A6A1A03041989"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although frailty assessment is crucial for understanding critically ill patients' prognosis, traditional frailty measures require substantial efforts and time from health care professionals. To address this limitation, the laboratory frailty index (FI\u2010LAB) based on laboratory clinical data was developed. However, knowledge regarding its correlation with health outcomes among critically ill older patients is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To identify the association between the FI\u2010LAB and acute, mid\u2010 and long\u2010term outcomes among critically ill older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>This retrospective correlational study used electronic health records of 2106 older patients who were admitted to the intensive care unit at a tertiary hospital in Seoul, Korea. Acute and mid\u2010term outcomes included occurrence of delirium and in\u2010hospital mortality, and the long\u2010term outcome included 1\u2010year mortality. Logistic regression was used to explore the relationships across FI\u2010LAB, delirium, and in\u2010hospital mortality, while Cox proportional hazard regression was used to analyse the relationship between FI\u2010LAB and 1\u2010year mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Frailty assessed by FI\u2010LAB was significantly associated with increased risk of delirium (odds ratio [OR]\u2009=\u20096.21, 95% confidence interval [CI]\u2009=\u20092.31\u201325.39,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.009), in\u2010hospital mortality (OR\u2009=\u20092.38, 95% CI\u2009=\u20091.15\u20135.79,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.014), and 1\u2010year mortality (hazard ratio\u2009=\u20092.47, 95% CI\u2009=\u20091.16\u20135.25,\n                      <jats:italic>p\u2009=<\/jats:italic>\n                      \u2009.019) after controlling for covariates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study highlighted the importance of using FI\u2010LAB for screening frailty in critically ill older adults. Health care providers can improve patients' acute, mid\u2010 and long\u2010term outcomes to develop more individualised management plans based on FI\u2010LAB scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance to Clinical Practice<\/jats:title>\n                    <jats:p>The FI\u2010LAB score calculated from routine laboratory data can be used by nurses as a screening tool to identify frail older adults in critical care. Early detection of frailty would allow for closer monitoring and the implementation of interventions to reduce delirium and mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nicc.13222","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T02:09:40Z","timestamp":1736215780000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association between laboratory data\u2010based frailty index and clinical health outcomes in critically ill older patients: A retrospective correlational study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8427-939X","authenticated-orcid":false,"given":"Hyunju","family":"Ji","sequence":"first","affiliation":[{"name":"Severance Hospital, Yonsei University Health System  Seoul Republic of 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