{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T04:59:04Z","timestamp":1780894744152,"version":"3.54.1"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072134"],"award-info":[{"award-number":["82072134"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Tight blood glucose monitoring is crucial in the management of intensive care unit (ICU) delirium because glycaemic disorders were suggested as initiating risk factors. However, the association between the frequency of fingertip blood glucose measurement (FFBGM) owing to tight blood glucose monitoring and delirium in ICU patients remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study aimed to investigate the association between FFBGM and the risk of delirium among ICU patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>This retrospective cohort study included 28\u2009553 adult ICU patients from the Medical Information Mart for Intensive Care (MIMIC)\u2010IV database. Delirium was identified using the Confusion Assessment Method for the ICU tool. Multivariable logistic regression, restricted cubic spline regression, sensitivity analyses and subgroup analyses were used to evaluate the association between FFBGM frequency and ICU delirium.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 28\u2009553 participants, 9599 (33.60%) developed delirium. The participants were categorised into three cohorts based on tertile\u2010derived thresholds for Total, Daytime and Nighttime FFBGM. Logistic regression analysis revealed a direct link between FFBGM and an increased incidence of critical delirium in ICU patients for each of the three variables (Total FFBGM Q3 vs. Q1: odds ratio [OR]\u2009=\u20091.25, 95% confidence interval [CI]: 1.18\u20131.32; Daytime FFBGM Q3 vs. Q1: OR\u2009=\u20091.21, 95% CI: 1.14\u20131.29; Nighttime FFBGM Q3 vs. Q1: OR\u2009=\u20091.17, 95% CI: 1.11\u20131.24). Sensitivity analysis, excluding diabetic and sedated patients, confirmed the robustness of the results. Furthermore, subgroup analysis showed consistent associations across demographic and clinical subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Increased FFBGM was independently associated with an increased risk of delirium among ICU patients. This finding suggests that FFBGM could serve as an independent predictor for delirium risk assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance to Clinical Practice<\/jats:title>\n                    <jats:p>This study may enhance nurses' awareness of the potential impact of FFBGM on delirium risk. It supports collaborative decision\u2010making between nurses and physicians to balance glycaemic control with patient comfort and to optimise monitoring strategies in ICU care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nicc.70128","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T09:53:02Z","timestamp":1754473982000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Association Between Frequency of Fingertip Blood Glucose Measurement and Delirium in Intensive Care Unit Patients: A Retrospective Study Based on the\n                    <scp>MIMIC<\/scp>\n                    \u2010\n                    <scp>IV<\/scp>\n                    Database"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1773-7452","authenticated-orcid":false,"given":"Jian","family":"Wei","sequence":"first","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiyuan","family":"Liang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Intelligent Computing and Signal Processing Ministry of Education, Anhui University  Hefei Anhui Province China"},{"name":"School of Integrated Circuits, Anhui University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Gao","sequence":"additional","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Cao","sequence":"additional","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanguo","family":"Dong","sequence":"additional","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Ji","sequence":"additional","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siying","family":"Liu","sequence":"additional","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianfeng","family":"Hua","sequence":"additional","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Intelligent Computing and Signal Processing Ministry of Education, Anhui University  Hefei Anhui Province China"},{"name":"School of Integrated Circuits, Anhui University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yang","sequence":"additional","affiliation":[{"name":"The Second Department of Critical Care Medicine The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"},{"name":"Laboratory of Cardiopulmonary Resuscitation and Critical Care The Second Affiliated Hospital of Anhui Medical University  Hefei Anhui Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,6]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2211868"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1007"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004313"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004066"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2011.11.016"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/2110\u20105820\u20102\u201049"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134\u2010023\u201007029\u20104"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.03.030"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S325365"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S369457"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jointm.2022.06.001"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S338712"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323000703500511"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019\u2010021\u201001456\u20104"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877\u2010022\u201002935\u20106"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0205637"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp\u20102019\u2010000411"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000610"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40779\u2010021\u201000338\u2010z"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jebm.12373"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.12638"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3182746442"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010079X.2007.00460.x"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134\u2010022\u201006650\u2010z"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246\u2010200107000\u201000012"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2020.11.011"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra052321"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc9333"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003299"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12050760"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iccn.2021.103111"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.129.6.1468"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054\u2010015\u20100855\u20103"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/nicc.12934"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iccn.2022.103348"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41999\u2010019\u201000281\u20102"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/phar.2223"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2019.08.022"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134\u2010023\u201007297\u20100"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.549908"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060521990502"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.4266\/acc.2022.00094"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010191217"},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/s19040800"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1109\/JSEN.2020.3025826"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22020638"}],"container-title":["Nursing in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nicc.70128","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nicc.70128","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nicc.70128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T04:23:49Z","timestamp":1780892629000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nicc.70128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,6]]},"references-count":46,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/nicc.70128"],"URL":"https:\/\/doi.org\/10.1111\/nicc.70128","archive":["Portico"],"relation":{},"ISSN":["1362-1017","1478-5153"],"issn-type":[{"value":"1362-1017","type":"print"},{"value":"1478-5153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,6]]},"assertion":[{"value":"2025-04-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70128"}}