{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:11:44Z","timestamp":1789164704933,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004410","name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu","doi-asserted-by":"publisher","award":["224S836"],"award-info":[{"award-number":["224S836"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Medical adhesive\u2010related skin injuries (MARSI) are a common complication in paediatric critical care, especially in patients with central venous catheters (CVCs). Despite the frequent use of medical adhesives, they are often underrecognised but are a preventable complication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of this study is to assess the effectiveness of the SECURE Care Bundle in preventing MARSI associated with CVC fixation in paediatric patients and its impact on the time to MARSI onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>\n                      This study is designed as a quasi\u2010experimental, pre\u2010test and post\u2010test control group study conducted in a Paediatric Cardiac Intensive Care Unit. A total of 92 neonatal and paediatric patients will be included. After obtaining consent from parents or legal guardians and assent from the children aged 7\u2009years and older when applicable, patients will be assigned to the pre\u2010test (control) group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200946) and the post\u2010test (intervention) group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200946). During the pre\u2010test phase, standard care will be provided according to the clinic's routine CVC procedures. In the post\u2010test phase, the SECURE Care Bundle will be implemented in addition to standard care. The bundle includes skin assessment, ensuring secure fixation without causing skin injury, adhesive selection, correct application and removal techniques, use of a silicone\u2010based adhesive remover and documentation of MARSI. Data will be collected using the descriptive information form, Braden QD Scale, skin observation form and SECURE Care Bundle checklist.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study will report the incidence of MARSI associated with CVC fixation and the time to onset of MARSI in paediatric patients by comparing the pre\u2010test (control) and post\u2010test (intervention) groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study is designed to evaluate the effectiveness of the SECURE Care Bundle in preventing MARSI in paediatric critical care. The proposed research may contribute to the development of a standardised approach to CVC fixation and protection of skin integrity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance to Clinical Practice<\/jats:title>\n                    <jats:p>This planned study will explore a structured approach to MARSI prevention in paediatric critical care units (PCCUs). The findings are intended to inform the development of standardised practices that support patient care and reduce the risk of MARSI. The SECURE Care Bundle may provide a framework to guide future efforts to protect skin integrity and minimise complications.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      The study is designed as a quasi\u2010experimental study with a pre\u2010test and post\u2010test control group design. This study has been registered at\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      (NCT06122402)\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nicc.70226","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T03:22:57Z","timestamp":1762399377000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>SECURE<\/scp>\n                    Care Bundle to Prevent Medical Adhesive\u2010Related Skin Injury in Paediatric Central Venous Catheter Fixation: A Study Protocol"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7709-7021","authenticated-orcid":false,"given":"\u00d6zlem","family":"\u015eensoy","sequence":"first","affiliation":[{"name":"School of Nursing, Department of Pediatric Nursing Istanbul University  Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8768-9282","authenticated-orcid":false,"given":"Seda","family":"\u00c7a\u011flar","sequence":"additional","affiliation":[{"name":"Florence Nightingale Faculty of Nursing Istanbul University\u2010Cerrahpa\u015fa  Istanbul 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